阿莫西林克拉维酸钾联合阿奇霉素治疗儿童上呼吸道细菌感染的临床疗效研究

Comparison of the Clinical Efficacy of Amoxicillin Clavulanate Potassium Combined with Azithromycin in the Treatment of Upper Respiratory Tract Bacterial Infections in Children

研究阿莫西林克拉维酸钾联合阿奇霉素治疗儿童上呼吸道细菌感染的疗效。选取2021年2月—2023年2月贵州省铜仁市思南县人民医院收治的98例上呼吸道细菌感染患儿为研究对象,随机将其分为对照组和观察组,每组各49例。对照组采取阿莫西林克拉维酸钾治疗,观察组在对照组基础上联合使用阿奇霉素治疗,对比两组患儿治疗效果,PCT、CRP、IL-6水平,不良反应发生率。结果显示,观察组治疗效果优于对照组,PCT、CRP、IL-6水平优于对照组,不良反应发生率低于对照组(P<0.05)。研究发现,针对儿童上呼吸道细菌感染患儿采用阿莫西林克拉维酸钾联合阿奇霉素治疗效果显著,其能够显著降低患儿各项感染指标,缩短患儿病程,加快患儿恢复。

To study the effects of amoxicillin potassium clavulanate combined with azithromycin on with upper respiratory tract bacterial infections.A total of 98 children with upper respiratory tract bacterial infection who were admitted to Sinan County People’s Hospital of Tongren City,Guizhou Province from February 2021 to February 2023 were selected as the research subjects,and they were randomly divided into control group and observation group,with 49 cases in each group.The control group was treated with amoxicillin potassium clavulanate,and the observation group was treated with azithromycin on the basis of the control group,and the treatment effect,PCT,CRP,IL-6 levels,and the incidence of adverse reactions were compared between the two groups.The results showed that the treatment effect of the observation group was better than that of the control group,the levels of PCT,CRP and IL-6 were better than those of the control group,and the incidence of adverse reactions was lower than that of the control group(P<0.05).Studies have found that amoxicillin clavulanate potassium combined with azithromycin has a significant effect on the treatment of children with upper respiratory tract bacterial infection,which can significantly reduce the infection indicators,shorten the course of the disease,and speed up the recovery of children.