摘要
For decades,researchers have sought a convenient,reliable,and fast track to drug development.Usually,it takes about 12–15 years from the initial drug discovery stage to the point at which the drug gets approval by national drug administration agencies.Moreover,when we consider the costs of both successful and failed programs,it costs about 2.5 billion US dollars to bring a drug to market(Figure 1).How to reduce the time and costs required for drug development is a subject that we are always thinking deeply about.
基金
supported by the National Key Research and Development Program of China(2021YFC2300200 and 2021YFC2300700)
the National Natural Science Foundation of China(NSFC)(32192452 and 82241076)。