黄连主要活性成分含量及影响因素研究进展

Research Progress on Content and Influencing Factors of MainActive Ingredients of Coptis chinensis

药用植物有效成分及其含量是评价药材质量的关键指标和临床疗效发挥的物质基础。黄连具有较高的药用价值,是重要的道地药材之一。近年来,黄连市场需求量的不断增加和过度采伐致使野生黄连资源濒临枯竭,人工栽培成为保障市场需求的重要途径。为黄连资源保护和高效开发利用提供参考,通过系统梳理近年来发表的与黄连主要活性成分研究相关的文献,整合分析黄连主要活性成分种类和含量特征,重点分析生物因素和非生物因素对其有效活性成分含量的影响,探讨相关研究存在的问题与瓶颈,并展望未来黄连的研究方向。

The active ingredients of medicinal plants and their contents are the key indicators for evaluating the quality of medicinal materials and the material basis for clinical efficacy.Coptis chinensis has high medicinal value,which is one of the important genuine medicinal materials.Wild C.chinensis resources are on the verge of exhaustion due to increasing market demand and over-harvesting,therefore,artificial cultivation has become an important way to ensure market demand.In order to provide a reference for C.chinensis resource protection and efficient development and utilization,the research literature related to the main active ingredients of C.chinensis published in recent years was systematically reviewed,the types and content characteristics of the main active ingredients of C.chinensis were integrated and analyzed,the influences of biological and abiotic factors on the content of the effective active ingredients were analyzed,the existing problems and bottlenecks of related research were discussed,and the future research direction of C.chinensis was prospected as well.