中西医结合治疗慢性乙型肝炎的本体构建研究

Ontological framework for integrative treatment of Chronic hepatitis B with chinese and western medicine

目的:为了给中西医结合治疗慢性乙型肝炎(CHB)提供更加全面、综合的治疗策略,形成系统化和结构化的知识体系,辅助实现知识的共享与交互,构建一个融合中西医结合治疗理念、方法和实践的CHB本体知识库。方法:基于斯坦福医学院本体七步法,以网络本体语言(OWL)为描述语言,使用Protégé5.6.0本体编辑工具,构建中西医结合治疗CHB本体,并使用推理机HermiT进行推理完成本体一致性检验。结果:所构建的中西医结合治疗CHB本体共有类44个,对象属性12个,数据属性128个,实例509个,基本实现了对中西医结合治疗CHB领域知识的语义化表达。结论:通过中西医结合治疗CHB本体构建,实现了中西医结合治疗CHB的知识推理和共享,并为中西医结合治疗CHB相关领域知识图谱的构建及其智能化应用研究提供支撑。

Objective:This study aims to construct an ontology knowledge base for Chronic Hepatitis B(CHB) within an integrated system of Traditional Chinese and Western medicine.It seeks to form a systematic and structured knowledge framework to facilitate the sharing and interaction of knowledge,thereby offering more comprehensive and holistic treatment strategies for the integrated approach to CHB therapy.Methods:Following the seven-step ontology method developed by Stanford School of Medicine,the network ontology language OWL was employed as the descriptive framework,while the Protege 5.6.0 ontology editing tool facilitated the construction of an integrated traditional Chinese and Western medicine treatment for CHB.The HermiT reasoner was then utilized to ensure consistency within the ontology.Results:The ontology includes 44 classes,509 instances,12 object properties,along with 128 datatype properties.This construction effectively achieves the semantic representation of knowledge in the field of CHB treatment from both TCM and western medicine perspectives.Conclusion:The construction of the integrated ontology for CHB treatment facilitates knowledge reasoning and sharing between TCM and western medicine.It supports the development of knowledge maps and research on intelligent applications in the field of CHB treatment,enhancing the synergy between these two medical systems.