陈皮化学成分与药理活性研究进展

Research Progress on Chemical Constituents and Pharmacological Effects of Citri Reticulatae Pericarpium

陈皮最早载于《神农本草经》,被列为上品,具有理气健脾,燥湿化痰等功效,主要用于脘腹胀满,食少吐泻,咳嗽痰多等临床症状。作为一种常见的药食两用中药,其应用非常广泛。陈皮包含多种有效活性成分,包括萜与挥发油、黄酮、生物碱和其他成分;多种药理学研究表明陈皮具有抗炎、抗肿瘤、抗氧化、对心血管系统的影响和其他作用等多种药理学作用。因此本文对陈皮的化学成分和药理活性进行综述,以期对陈皮后续相关研究提供科学理论依据。

Citri Reticulatae Pericarpium(Chenpi)was first listed in the Sheng Nong's herbal classic,and is classified as a high quality product with the ability to regulate qi and strengthen the spleen,dry dampness and disperse phlegm,etc.It is mainly used for the clinical symptoms of bloating and fullness in the stomach and abdomen,poor appetite,vomiting,diarrhoea,and coughing with excessive phlegm.As a common dual-use traditional Chinese medicine,it has a wide range of applications.Chenpi contains a variety of active ingredients,including terpenes and volatile oils,flavonoids,alkaloids and other components;various pharmacological studies have shown that Chenpi has a variety of pharmacological effects,such as anti-inflammatory,anti-tumour,antioxidant,cardiovascular effects and other effects.Therefore,this paper reviews the chemical constituents and pharmacological activities of Chenpi in order to provide a scientific theoretical basis for the subsequent studies on Chenpi.