急性主动脉夹层患者临床结局分析及相关因素调查

Analysis of clinical outcomes and investigation of related factors in patients with acute aortic dissection

目的 调查急性主动脉夹层患者临床结局及相关因素分析。方法 回顾性分析2018年1月至2023年3月在新乡医学院第三附属医院收治的76例急性主动脉夹层患者的临床资料,根据收治后三月内患者是否发生死亡分为死亡组和生存组,其中死亡组25例,生存组51例。比较两组患者的基线情况、治疗方式、并发症及Stanford分型等,logistic方法对影响急性主动脉夹层患者发生死亡的影响因素进行分析。结果 生存组高血压人数占比低于死亡组,并且生存组和死亡组在Stanford分型方面具有差异(P<0.05);进一步通过统计分析得出,生存组与死亡组患者在主动脉直径、内膜破口位置等方面的差异具有统计学意义(P<0.05);死亡组患者的术后并发症人数占比高于生存组(P<0.05);logistic结果显示,高血压、术后并发症、Stanford分型为A型均为急性主动脉夹层患者发生死亡结局的独立危险因素(P<0.05)。结论 多个因素会影响急性主动脉夹层患者的临床结果,包括高血压、手术后的并发症以及Stanford A型分型,这些均是导致急性主动脉夹层患者死亡的独立风险因素。

Objective To investigatie of clinical outcomes and related factors in patients with acute aortic dissection.Methods Retrospective analysis of clinical data of 76 patients with acute aortic dissection admitted to the Third Affiliated Hospital of Xinxiang Medical College from January 2018 to March 2023,according to whether the patient died within three months of admission,they were divided into a death group and a survival group,with 25 cases in the death group and 51 cases in the survival group.Compare baseline conditions,treatment methods,complications,and Stanford classification between two groups of patients.The logistic method was used to analyze the influencing factors of mortality in patients with acute aortic dissection.Results The proportion of people with hypertension in the survival group was lower than that in the death group,and there was a difference in Stanford classification between the survival group and the death group(P<0.05).Further statistical analysis showed that the patients in the survival group and the death group had statistically significant differences in aorta diameter and the location of the intimal breach(P<0.05);the proportion of postoperative complications in the death group is higher than that in the survival group(P<0.05);the logistic results showed that hypertension,postoperative complications,and Stanford type A were all independent risk factors for mortality in patients with acute aortic dissection(P<0.05).Conclusion Multiple factors can affect the clinical outcomes of patients with acute aortic dissection,including hypertension,postoperative complications,and Stanford A typing,all of which are independent risk factors for mortality in patients with acute aortic dissection.