穴位注射联合中药贴敷在妊娠剧吐中的应用研究

Application study of acupoint injection combined with traditional Chinese medicine patches in the treatment of hyperemesis gravidarum

目的探讨穴位注射联合中药贴敷在妊娠剧吐中的应用效果。方法选取2021年8月至2023年8月滁州市中西医结合医院收治的72例妊娠期剧吐患者,采用随机数字表法分为观察组和对照组,每组36例。对照组以维生素B1注射液静脉滴注治疗,观察组在对照组基础上增加穴位注射联合中药贴敷治疗。评估两组患者的临床疗效、中医证候积分、呕吐量表评分、焦虑抑郁状况评分、生化指标和治疗安全性。结果观察组总有效率(91.67%)高于对照组患者(72.22%),差异有统计学意义(P<0.05)。治疗后,观察组主要中医证候积分(恶心呕吐、口干烦渴、头胀而晕、舌红苔黄评分)、妊娠期恶心呕吐专用量化表(PUQE)、焦虑自评量表(SAS)、抑郁自评量表(SDS)评分均低于对照组。观察组血钾、血钠、血清白蛋白水平高于对照组,尿酮体水平低于对照组,差异均有统计学意义(P<0.05)。治疗期间两组不良反应发生率(13.88%vs.11.11%)比较,差异无统计学意义(P>0.05)。结论穴位注射联合中药贴敷在妊娠剧吐中的应用效果良好,能够提高疗效,改善中医证候和呕吐症状,改善负性情绪,提高患者的电解质、白蛋白水平,降低尿酮体水平,治疗安全性良好。

Objective To investigate the application effect of acupoint injection combined with traditional Chinese medicine patches in the treatment of hyperemesis gravidarum.Methods 72 patients with hyperemesis gravidarum admitted to Chuzhou Integrated Traditional Chinese and Western Medicine Hospital from August 2021 to August 2023 were randomly divided into an observation group and a control group,with 36 cases in each group by random number table method.The control group was treated with intravenous infusion of vitamin B1 injection,while the observation group was treated with acupoint injection combined with traditional Chinese medicine patches in addition to the control group.Evaluated the clinical efficacy,traditional Chinese medicine symptom score,vomiting scale score,anxiety and depression status score,biochemical indicators and treatment safety of two groups of patients.Results The total effective rate of the observation group(91.67%)was higher than that of the control group(72.22%),the difference was statistically significant(P<0.05).After treatment,the main traditional Chinese medicine symptom scores(nausea and vomiting,dry mouth and thirst,head swelling and dizziness,tongue redness and yellow coating scores),pregnancy specific nausea and vomiting quantification scale(PUQE),self rating anxiety scale(SAS),and self rating depression scale(SDS)scores of the observation group were lower than those of the control group.The levels of blood potassium,blood sodium,and serum albumin in the observation group were higher than those in the control group,while the levels of urinary ketones were lower than that in the control group,the differences were statistically significant(P<0.05).There was no statistically significant difference in the incidence of adverse reactions between the two groups during treatment(13.88%vs.11.11%)(P>0.05).Conclusion The application of acupoint injection combined with traditional Chinese medicine patches in hyperemesis gravidarum has a good effect,which can improve the therapeutic effect,improve traditional Chinese medicine symptoms and vomiting symptoms,improve negative emotions,increase the patient's electrolyte and albumin levels,reduce urinary ketone levels,and ensure good treatment safety.