信迪利单抗联合安罗替尼治疗PD-L1阳性肺肉瘤样癌1例并文献复习

A case of PD-L1-positive pulmonary sarcomatoid carcinoma treated with sindilizumab in combination with anilotinib and literature review

该文报道1例78岁男性晚期肺肉瘤样癌患者,PD-L1阳性表达,该患者通过联合使用信迪利单抗和安罗替尼进行治疗,疗效达到部分缓解(PR),无进展生存期(PFS)达到30个月。治疗过程中出现了2级高血压和其他短暂的心脏问题,但整体生活质量良好。

This article reports on a 78-year-old male patient with advanced pulmonary sarcomatoid carcinoma with positive PD-L1 expression,who achieved partial remission(PR)and progression-free survival(PFS)of 30 months with sindilizumab and amilorotinib.Grade 2 hypertension and other transient cardiac problems occurred during treatment,but overall quality of life was good.