桑枝总生物碱治疗痰浊瘀阻型糖尿病肾病的临床疗效观察

Clinical Observation of Total Alkaloids from Mulberry Branches on the Treatment of Diabetes Nephropathy with Phlegm Turbid and Blood Stasis

目的:观察桑枝总生物碱治疗痰浊瘀阻型糖尿病肾病的临床疗效。方法:对2022年1月-2022年12月安徽中医药大学第一附属医院及淮北市中医院、安庆石化医院等多家医院门诊收治的90例痰浊瘀阻型糖尿病肾病患者的病例资料进行回顾性分析,随机分为治疗组和对照组,对比临床疗效、中医证候评分改善及相关血液指标改善情况等。结果经过治疗后,治疗组中医临床疗效明显优于对照组,两组在中医证候评分、肾功能相关指标、血糖血脂相关指标指标等方面均有着明显改善,治疗组各方面指标的改善程度上明显高于对照组。结论桑枝总生物碱治疗痰浊瘀阻型糖尿病肾病临床疗效显著,对于中医证候评分、肾功能相关指标、血糖血脂相关指标均有着明显的改善效果,同时还可以缓解临床症状,提高患者生活质量。

Objective To observe the clinical efficacy of total alkaloids of Ramulus Mori in the treatment of diabetes nephropathy of phlegm stasis type.Methods Retrospective analysis was made on the clinical data of 90 patients with diabetes nephropathy of phlegm turbid and blood stasis type who were admitted to the primary hospital affiliated with Anhui University of Traditional Chinese Medicine,Huaibei Hospital of Traditional Chinese Medicine,Anqing Petrochemical Hospital and other hospitals from January 2022 to December 2022.They were assigned to either the treatment group or the control group at random.The clinical efficacy,TCM syndrome score and related blood indicators were compared.Results After treatment,The treatment group demonstrated notably superior clinical efficacy when treated with traditional Chinese medicine,compared to the control group.Both groups showed significant improvements in traditional Chinese medicine syndrome scores,kidney function related indicators,blood glucose and lipid related indicators,and the degree of improvement in various indicators was significantly greater in the treatment group than in the control group.Conclusion The total alkaloids of mulberry twigs have a significant clinical effect in the treatment of phlegm turbid and blood stasis type diabetes nephropathy,which has significantly improved the TCM syndrome score,renal function related indicators,blood glucose and lipid related indicators,and can also alleviate clinical symptoms and improve the quality of life of patients.