重症急性胰腺炎的早期精准诊疗进展

Advances in early precision diagnosis and treatment of severe acute pancreatitis

重症急性胰腺炎(SAP)是一种起病急骤、病情复杂的消化系统急症,常伴有严重的局部和全身并发症,病死率较高。近年来,随着治疗理念的不断更新,尤其是内镜和外科微创技术的不断进步,SAP患者的预后得到明显改善。但临床上,尤其在病程早期,仍普遍存在不规范、不精准的诊疗行为,这是病程后期出现严重并发症的重要原因之一,也是SAP患者预后不佳的主要原因之一。鉴于此,本文系统回顾近年高质量文献,并结合笔者团队的最新临床研究成果,总结SAP早期精准诊疗方面的进展,为SAP的规范化诊疗提供新的依据,必将有助于进一步提高SAP的总体治疗效果。

Severe acute pancreatitis(SAP)is a rapid onset and complex acute digestive system emergency,often accompanied by severe local and systemic complications,leading to a high mortality rate.In recent years,with the continuous update of treatment concepts,especially the advancement of endoscopic and minimally invasive surgical techniques,the prognosis of SAP patients has significantly improved.However,in clinical practice,particularly in the early stages of the disease,there are still widespread issues of non-standard and imprecise diagnostic and therapeutic practices,which are important factors contributing to the occurrence of severe complications in the later stages of the disease and a major reason for the poor prognosis of SAP patients.In light of this,this article systematically reviews highquality literature from recent years and combines the latest clinical research findings from the authors'team to summarize advancements in early precise diagnosis and treatment of SAP,providing new evidence for standardized treatment of SAP,which will undoubtedly help further improve the overall treatment outcomes for SAP.