发酵中草药提升母猪抗病性能的应用研究

Research on the Application of a Fermented Traditional Chinese Medicine to Enhance the Disease Resistance of Sows

为评估一款发酵中草药对被毛粗糙无光泽、消瘦、泪斑重、背部毛孔有出血点等症状的母猪(统称亚健康母猪)健康状况和繁殖性能的改善效果。选取处于亚健康状态的母猪60头,按照单因素设计分为3组(A、B、C组),A组作为对照不添加发酵中草药,B组发酵中草药按3 kg/t添加,C组发酵中草药按6 kg/t添加,初次使用15 d,间隔20 d,再次使用15 d。分别在母猪妊娠50日龄(P50)、分娩当日(N0)、分娩后25 d(N25)采血5 mL备检,仔猪于分娩当天和25日龄断奶当天采血1~2 mL备检。临床观察结果显示,在使用发酵中草药后母猪的泪斑、出血点等症状得到明显改善,皮毛光泽度得到提升;采样评估结果显示,该款发酵中草药可以有效提高母猪免疫球蛋白A(IgA)、免疫球蛋白G(IgG)、免疫球蛋白M(IgM)的含量,降低促炎因子白细胞介素-6(IL-6)和白细胞介素-8(IL-8)的水平,提升超氧化物歧化酶(SOD)和谷胱甘肽过氧化物酶(GSH-Px)的水平。该发酵产品能改善动物机体的抗氧化功能,增强机体免疫力,有利于改善母猪的亚健康状态。

To evaluate the effect of a fermented traditional Chinese medicine on the health condition and reproductive performance of sows with rough and lusterless coats,lethargy,heavy tear spots,and hemorrhagic dorsal pores(collectively referred to as subhealthy sows).Sixty sows in subhealthy condition were selected and divided into three groups(Group A,B and C)according to a one-way de-sign;Group A was used as a control without the use of fermented herbs,Group B was added with 3 kg/t of fermented herbs,and Group C was added with 6 kg/t of fermented herbs,and the herbs were used for 15 d at first application,then for 20 d at intervals,and then a-gain for 15 d.Blood was collected from sows on the 50th day of gestation(P50),on the day of farrowing(N0),and 25 d after farrowing(N25).5 mL of blood was collected at 50 days of gestation(P50),on the day of farrowing(N0),and 25 days after farrowing(N25),and 1~2 mL of blood was collected on the day of farrowing and the day of weaning at 25 days of age of piglets.Clinical observation showed that the use of the fermented herbal medicine improved the symptoms of tear spots and hemorrhagic spots of sows,and the glossiness of the coat was improved;sampling evaluation showed that the fermented herbal medicine could effectively increase the content of im-munoglobulin A(IgA),immunoglobulin G(IgG)and immunoglobulin M(IgM),and reduce the content of pro-inflammatory factors inter-leukin-6(IL-6)and interleukin-8(IL-8).interleukin-8(IL-8),and elevated the levels of superoxide dismutase(SOD)and glutathione peroxidase(GSH-Px).The fermentation product could improve the antioxidant function of the body,enhance the immunity of the body,and help to improve the subhealth state of sows.