股四头肌厚度与机械通气患者首次撤机结局的相关性研究

Correlation Analysis of Quadriceps Thickness and the Outcome of First Initial Weaning from Mechanical Ventilation in Patients

目的:本研究旨在探讨机械通气患者股四头肌厚度(QMT)与首次撤机结局之间的相关性。方法:收集2023年6月至2024年6月苏州大学附属第一医院重症医学科(ICU)收治的机械通气危重患者166例,根据首次撤机结局分为成功组(n=122)和失败组(n=44),比较两组之间的QMT及其变化,并将QMT变化率与浅快呼吸指数(RSBI)进行相关性分析,探寻其首次撤机结局与股四头肌厚度变化之间的关系。结果:与撤机成功组相比,撤机失败组QMT变化率明显增高(P<0.05);QMT变化率与RSBI具有相关性,呈显著正相关(r=0.651,P<0.05)。结论:QMT变化率可以预测机械通气患者首次撤机结局,对于撤机失败有一定的预测价值。

Objective:The aim of this study was to investigate the correlation between quadriceps thickness(QMT)and the outcome of first withdrawal in patients with mechanical ventilation.Methods:A total of 166 critically ill patients with mechanical ventilation admitted to the Intensive Care Unit(ICU)of the First Affiliated Hospital of Soochow University from June 2023 to June 2024 were collected.According to the outcome of the first weaning,the patients were divided into a success group(n=122)and a failure group(n=44).QMT and its changes were compared between the two groups,and the correlation between QMT change rate and rapid shallow breathing index(RSBI)was analyzed.To explore the relationship between the outcome of the first withdrawal machine and the change of quadriceps thickness.Results:Compared with the successful weaning group,the QMT variation rate was significantly higher in the failed weaning group(P<0.05).The rate of QMT change was correlated with RSBI,with a significant positive correlation(r=0.651,P<0.05).Conclusion:The QMT variation rate may serve as a predictor for the outcome of the first weaning attempt in mechanically ventilated patients and holds potential predictive value for weaning failure.