胶原蛋白肽改善和延缓皮肤衰老作用功效及机制的研究进展

Research Progress on the Efficacy and Mechanism of Collagen Peptides in Delaying Skin Aging

随着社会老龄化问题的出现和人们对皮肤健康重视程度的提高,市场对预防和延缓皮肤衰老的活性成分需求不断增加。胶原蛋白肽具有多种生理活性,在延缓皮肤衰老方面具有很大潜力。本文介绍胶原蛋白肽的来源与制备、结构及生物活性,概述胶原蛋白肽在延缓皮肤衰老方面的作用机制,并综述近10年口服胶原蛋白肽改善皮肤衰老表现的相关临床试验研究进展。目前胶原蛋白肽已规模化应用到食品、口服美容饮品、保健品和化妆品等领域,但在最适摄入量、评价方法、功能肽段的鉴定和挖掘及与其他成分的相互作用等方面,仍存在一些问题和挑战需要解决,随着生产技术的进步和研究的不断深入,具有抗皮肤衰老活性的胶原蛋白肽在食品营养、保健美容、临床治疗和医疗美容等领域具有巨大的潜力和广阔的应用前景。

With the emergence of social aging and the increasing emphasis on skin health,the demand in the market for active ingredients to prevent and delay skin aging is increasing.Collagen peptides have various physiological activities and great potential in delaying skin aging.In this paper,the source,preparation,structure and biological activities of collagen peptides are introduced,and the mechanisms of action of collagen peptides in delaying skin aging are summarized.Moreover,the progress made in the past decade in clinic research on oral collagen peptides in alleviating skin aging is reviewed.At present,collagen peptides have been widely applied in various fields such as foods,oral beauty drinks,health products and cosmetics.However,there are still some problems and challenges in terms of optimal intake,evaluation methods,identification and exploration of functional peptides,and interaction with other components.With the progress of production technology and the continuous deepening of research,collagen peptides with anti-skin aging activity have enormous potential and broad application prospects in food nutrition,healthy skincare,clinical therapy and medical beauty.