固相萃取-电感耦合等离子体质谱法测定高盐食品中的12种重金属元素

Simultaneous Determination of Multiple Heavy Metals in High Salt Foods by Solid Phase Extraction-Inductively Coupled Plasma Mass Spectrometry

本研究建立了固相萃取-电感耦合等离子体质谱法,测定高盐食品中矾(V)、锰(Mn)、铁(Fe)、钴(Co)、镍(Ni)、铜(Cu)、锌(Zn)、镓(Ga)、镉(Cd)、锡(Sn)、铅(Pb)、铀(U)等12种重金属元素。样品经微波消解并赶酸后用1mol/L乙酸铵缓冲溶液调节pH值至5.0±0.5,通过固相萃取柱去除钠(Na)、钾(K)等干扰盐分,样品中的重金属元素则保留在萃取柱上,经2mol/L硝酸洗脱后,进入电感耦合等离子体质谱仪进行测定。本研究所建立的方法,能降低盐分对目标元素测定的干扰,定量准确,重现性好,适用于高盐食品中12种重金属元素的测定。

In this paper,a method based on solid phase extraction(SPE)and inductively coupled plasma mass spectrometry(ICPMS)detection was established for the determination of 12 heavy metal elements,including V,Mn,Fe,Co,Ni,Cu,Zn,Ga,Cd,Sn,Pb and U in high salt products.After the sample was digested by microwave digestion,the obtained sample solution was adjusted to pH 5.0±0.5 by using 1 mol/L ammonium acetate buffer solution.Then,iminodiacetic acid chelating resin packed SPE column was used to adsorb target metal ions and separate interfering salts(e.g.,Na+and K+).Diluted nitric acid(2 mol/L)was used for subsequent elution of target metal ions,followed by ICPMS detection.The established method can reduce the interference caused by salt in the matrix.It is featured with good reproducibility,and suitable for the determination of 12 heavy metal elements in high salt samples.