美洛西林钠舒巴坦治疗支气管肺炎的药学分析

Pharmaceutical analysis of meloxicillin sodium sulbactam in the treatment of bronchial pneumonia

目的研究支气管肺炎治疗中,美洛西林钠舒巴坦疗效,以期为后续治疗提供依据.方法选取肇庆市鼎湖区中医院2020年2月-2023年12月期间收治的68例支气管肺炎患者,按不同的治疗方式进行分组,每组34例,采取美洛西林钠治疗的患者作为对照组,以美洛西林钠舒巴坦治疗的患者作为研究组.比较两组疗效、临床症状改善时间、炎性因子、不良反应、肺功能.结果研究组临床症状改善时间短于对照组(P<0.05);组间炎性因子对比显示,两组均得到有效抑制,治疗后差异显示研究组各指标水平更低(P<0.05);研究组肺功能更高,差异有统计学意义(P<0.05);与对照组相比,研究组的不良反应发生率更低,差异有统计学意义(P<0.05);对照组治疗有效率低于研究组(P<0.05).结论美洛西林钠舒巴坦疗效好,用药后可以改善患者肺功能,加快疾病恢复进程,对炎性因子的抑制效果好,不良反应发生率低,利于疾病转归.

Objective To investigate the efficacy of mezzanine sodium and sulbactam in the treatment of bronchopneumonia,in order to provide a basis for subsequent treatment.Methods From February 2020 to December 2023,68 patients with bronchopneumonia were selected from Dinghu Traditional Chinese Medicine Hospital in Zhaoqing City,all of whom underwent surgical treatment.According to a random number table,different treatment methods were divided into two groups(n=34).The control group received treatment with meropenem sodium,while the study group received treatment with meropenem sodium and sulbactam.Analyze the efficacy,clinical symptom improvement time,inflammatory factors,adverse reactions,and lung function of two groups.Results The improvement time of clinical symptoms in the study group was shorter than that in the control group(P<0.05);the comparison of inflammatory factors between groups showed that both groups were effectively inhibited,and the difference after treatment showed that the levels of various indicators in the study group were lower(P<0.05);the lung function of the research group was higher,and the analysis was meaningful(P<0.05);compared with the control group,the incidence of adverse reactions in the study group was significantly lower(P<0.05);the effective rate of treatment in the control group was lower than that in the study group(P<0.05).Conclusion Meroxicillin sodium sulbactam has good therapeutic effects,can improve patients'lung function,accelerate disease recovery process after medication,has good inhibitory effect on inflammatory factors,low incidence of adverse reactions,and is conducive to disease progression.