脓毒血症致新发心房颤动的研究进展

Research Progress of New Atrial Fibrillation Caused by Sepsis

脓毒血症是由感染引起的全身炎性反应综合征,其发病与机体对感染性因素的异常反应密切相关。心房颤动(简称房颤)是临床常见的心律失常,会影响心脏功能,导致血栓形成。脓毒血症患者机体出现的全身炎性反应,可能会导致心脏功能受损,引发房颤。脓毒症、低钾血症、急性充血性心力衰竭和新发非房颤心律失常是新发房颤的独立危险因素。该文对近年来关于脓毒血症患者新发房颤的发生机制、影响因素、识别诊断及治疗管理的研究进行综述,为脓毒血症的预防管理提供科学依据。

Sepsis is a systemic inflammatory response syndrome caused by infection,and its pathogenesis is closely related to the abnormal response of the body to infectious factors.Atrial fibrillation(AF)is a common clinical arrhythmia that affects heart function and leads to the formation of blood clots.The systemic inflammatory response in patients with sepsis may lead to impaired heart function and atrial fibrillation.Sepsis,hypokalemia,acute congestive heart failure and new non-atrial arrhythmias are independent risk factors for new atrial fibrillation.This article reviews the recent studies on the pathogenesis,influencing factors,identification,diagnosis and management of new atrial fibrillation in patients with sepsis,and provides scientific basis for the prevention and management of sepsis.