中西医结合治疗恢复期支原体肺炎肺脾气虚证的临床效果分析

Clinical Effect of Integrated Traditional Chinese and Western Medicine on Lung Qi Deficiency Syndrome of Mycoplasma Pneumonia in Convalescent Period

目的:分析中西医结合治疗恢复期支原体肺炎肺脾气虚证的临床效果。方法:选取66例恢复期支原体肺炎肺脾气虚证患儿作为研究对象,均为高台县中医医院2020年8月—2022年4月收治,采用随机数字表法分组,每组33例。对照组采用阿奇霉素治疗,观察组在对照组基础上联合加味参芪补脾汤治疗。比较两组治疗效果、不良反应发生率、炎性因子水平及血气分析指标。结果:观察组治疗总有效率高于对照组,不良反应总发生率低于对照组(P<0.05)。治疗后,两组γ-干扰素、白细胞介素-4水平低于治疗前,且观察组低于对照组(P<0.05)。治疗后,两组动脉血氧分压、血氧饱和度均高于治疗前,且观察组高于对照组,两组动脉血二氧化碳分压均低于治疗前,且观察组低于对照组(P<0.05)。结论:中西医结合治疗恢复期支原体肺炎肺脾气虚证的临床效果较好,能够降低炎性因子水平,改善血气分析指标,降低不良反应发生率。

Objective:To analyze the clinical effect of integrated traditional Chinese and western medicine on lung Qi deficiency syndrome of mycoplasma pneumonia in convalesce period.Methods:A total of sixty-six children with pneumoqi deficiency syndrome of mycoplasma pneumonia in the convalescence-stage were selected as the study objects,all of whom were admitted to Gaotai County Hospital of Traditional Chinese Medicine from August 2020 to April 2022.They were divided by random number table method,with thirty-three cases in each group.The control group was treated with azithromycin,and the observation group was treated with supplemented Shenqi Bupi Decoction on the basis of control group.The therapeutic effect,incidence of adverse reactions,levels of inflammatory factors and blood gas analysis indexes were compared between the two groups.Results:The total effective rate of treatment in observation group was higher than that in control group,and the total incidence of adverse reactions was lower than that in control group(P<0.05);after treatment,the levels ofγ-interferon and interleukin-4 in two groups were lower than before treatment,and the observation group was lower than the control group(P<0.05);after treatment,the partial pressure of arterial blood oxygen and saturation of blood oxygen in both groups were higher than before treatment,and the observation group was higher than the control group,the partial blood pressure of carbon dioxide in both groups was lower than before treatment,and the observation group was lower than the control group(P<0.05).Conclusion:The clinical effect of integrated Chinese and western medicine on lung Qi deficiency syndrome of mycoplasma pneumonia in convalesce stage is good,which can reduce the level of inflammatory factors,improve blood gas analysis index and reduce the incidence of adverse reactions.