口服中成药说明书禁忌信息的调查

Investigation on Contraindicated Information of Oral Proprietary Chinese Medicines

目的 分析口服中成药说明书的禁忌特点,为临床合理用药提供一些参考。方法 收集新乡医学院第一附属医院2022年1月1日至2023年8月31日常用的217份口服中成药说明书,计算配伍禁忌、证候禁忌、用药人群禁忌及饮食禁忌的标注率,分析禁忌特点。结果 标注“禁忌信息”的说明书占55.30%(120/217),其中“用药人群禁忌”的标注率最高,为48.85%(106/217);“配伍禁忌”的标注率最低,为1.38%(3/217)。“孕妇禁用、慎用、忌用或在医生指导下服用”的标注率最高,为81.13%(86/106);“青春期及更年期在医生指导下服用”的标注率最低,为1.89%(2/106)。结论 临床用药需详细阅读禁忌信息,便于合理安全使用中成药。

Objective The contraindications of oral Chinese patent medicine instructions were analyzed to provide some references for clinical rational drug use.Methods A total of 217 instructions of oral proprietary Chinese medicines used in the First Affiliated Hospital of Xinxiang Medical University from January 1,2022 to August 31,2023 were collected.The labeling rates of incompatibility,syndrome contraindications,drug population contraindications and dietary contraindications were calculated,and the contraindications were analyzed.Results The instructions marked with“contraindicated information”accounted for 55.30%(120/217),and among which,48.85%(106/217)of the instructions marked with“drug population contraindicated”,which was the highest,the labeling rate of“incompatibility”was the lowest[1.38%(3/217)].The labeling rate of“forbidden,cautiously used,contraindicated or under the guidance of doctors in pregnant women”was the highest[81.13%(86/106)].The labeling rate of“adolescent and menopause should be taken under the guidance of doctors”was the lowest[1.89%(2/106)].Conclusion It is necessary to read the contraindicated information in detail for the rational and safe use of proprietary Chinese medicine.