两种常用品牌双能X线骨密度仪应用标准化中国库的检出率对比

Comparison of the detection rate of two commonly used brands of dual-energy X-ray bone densitometry in standardized Chinese database

目的回顾分析某三甲医院两种常用品牌双能X线吸收测量仪(dual energy X-Ray absorptiometry,DXA)应用标准化中国库(依据近期研究成果,首次试用)前后的骨质疏松检出率差异,以验证该标准化数据库的使用效果。为实现不同品牌DXA T值标准化提供理论和数据支持。方法收集2021年6月11日—2022年10月20日GE-Prodigy以及2021年10月1日—2022年9月9日Hologic Horizon-W测量的门诊30岁以上中国患者的骨密度结果。分别获得腰椎(L1~4)和单侧髋应用“中国库”和“标准化中国库”的T值,并依据T值计算两种品牌DXA应用标准化数据库前后的检出率。结果两种品牌DXA应用标准化数据库前后的L1~4检出率分别相差136.99%和4.58%;单侧髋检出率分别相差58.69%和22.99%。结论GE-Prodigy与Hologic Horizon-W对骨质疏松的检出率差异较大,标准化中国库的应1用降低了这两种国内常用品牌DXA的检出率的差异,将很大程度上提高骨质疏松诊断的同质性。

Objective The difference in the osteoporosis detection rate before and after the application of the standardized Chinese database(based on recent research results,the first trial)of two commonly used brands of dual-energy X-ray absorptiometer(DXA)in a third class hospital was reviewed and analyzed,so as to verify the application effect of the standardized database and provide theoretical and data support for the standardization of T values of different brands of DXA.Methods BMD results from out-patient Chinese patients over 30 years of age measured by GE-Prodigy from June 11,2021 to October 20,2022 and Hologic Horizon-W from October 1,2021 to September 9,2022 were collected.The T-values of lumbar spine(L1~4)and unilateral hip were obtained,and the detection rates of DXA before and after the application of the standardized database were calculated.Results The difference of L1~4 detection rates between the two brands before and after applying the standardized database was 136.99%and 4.58%,respectively.The detection rate of single hip was 58.69%and 22.99%respectively.Conclusion There were significant differences in the positive rates of osteoporosis between GE-Prodigy and Hologic Horizon-W.The application of standardized databases reduced the differences in positive rates between these two commonly used types of DXA devices in China and greatly improved the homogeneity of osteoporosis diagnosis.