成人支气管扩张症病因学诊断专家共识

Chinese expert consensus on the etiological diagnosis of adult bronchiectasis

支气管扩张症(简称支扩)是一种异质性很强的慢性气道疾病, 其病因诊断对于疾病管理具有重要作用。中国支气管扩张症临床诊治与研究联盟、中华医学会呼吸病学分会感染学组组织专家, 充分评估了支扩病因诊断领域最新的研究结果, 基于国际通用的Delphi程序, 经过多次会议讨论和修订, 最终形成了支扩病因学诊断的专家共识。本共识分为四个部分:支扩的定义及病因分类、支扩的病因学诊断程序、支扩的可治疗病因、支扩的其他病因。希望通过本共识, 助力提高中国支扩病因学诊断能力和疾病管理水平。

Bronchiectasis is a highly heterogeneous chronic airway disease for which accurate etiological diagnosis is crucial for effective management.A group of experts from the China Bronchiectasis Alliance and the Infection Assembly of the Chinese Thoracic Society conducted a comprehensive review of recent research into the etiology of bronchiectasis.Using the widely accepted Delphi methodology,the experts reached a consensus on the etiological diagnosis of bronchiectasis through multiple rounds of discussion and revision.The consensus is divided into four sections:the definition and classification of the etiology of bronchiectasis,the etiological diagnostic procedures for bronchiectasis,the treatable causes of bronchiectasis,and other causes of bronchiectasis.The ultimate goal of this consensus is to improve the diagnostic accuracy and optimize the management of bronchiectasis in China.The main recommendations of Section 1 focused on chest thin-section computed tomography(CT)for the diagnosis of bronchiectasis and the etiological classification.The main recommendations of Section 2 focused on the medical history collection for bronchiectasis and the etiological diagnostic protocol for bronchiectasis.The main recommendations of Section 3 focused on the recommendations of the diagnosis of bronchiectasis secondary to COPD,the diagnosis of bronchiectasis due to asthma,diffuse pan-bronchiolitis,allergic bronchopulmonary aspergillosis,connective tissue disease(CTD)-related bronchiectasis or gastroesophageal reflux disease(GERD)-related bronchiectasis.The main recommendations of Section 4 focused on suspected primary ciliary dyskinesia(PCD)-associated bronchiectasis,cystic fibrosis and the diagnosis of congenital airway malformations.