伴有t(16;17)染色体异常的APL样白血病1例报告并文献复习

APL-like leukemia with chromosomal translocation t(16;17):a case report and literature review

变异型急性早幼粒细胞白血病(APL)及APL样白血病均是APL中的少见类型,其中t(16;17)染色体异常更为罕见。本文报道1例伴有t(16;17)染色体异常及骨骼、淋巴结及中枢神经系统侵犯的APL样白血病患者,经过多周期化疗后获得完全缓解,随后进行造血干细胞移植,并进行文献复习。

Variant acute promyelocytic leukemia(APL)and APL-like leukemia are rare types of APL,with t(16;17)chromosome abnormality being even rarer.An APL-like patient with t(16;17)chromosome abnormality,which was characterized by bone,lymph node,and central nervous system involvement,was admitted to our hospital.He achieved complete remission after several cycles of chemotherapy and subsequently underwent hematopoietic stem cell transplantation.Furthermore,the diagnosis and treatment of this patient were reported and a literature review was conducted.