“三期三法”防治放射性肺损伤

Prevention and Treatment of Radiation-induced Lung Injury Based on the Theory of"Three Phases and Three Methods"

认为放射性肺损伤受放射线的热毒所引发,结合患者临床表现以及现代医学放射性肺损伤不同时期的病理特点,将放射性肺损伤病程分为热毒炽盛期、阴虚热蕴期、瘀血阻滞期三期,并根据分期提出不同治法。放射性肺损伤初期为热毒炽盛期,治以清肺解毒,常用银翘散加减治疗;中期为阴虚热蕴期,治以滋阴透热,常用自拟养阴清肺方治疗;晚期为瘀血阻滞期,治以活血化瘀,常用自拟清肺活血方治疗。

Radiation-induced lung injury(RILI)is caused by the"heat toxin"of radiation.Based on the clinical manifestation and the pathological characteristics of RILI in different phases in modern medicine,RILI is divided into three phases,that is intense heat toxin phase,yin deficiency and heat accumulation phase,and static blood obstruction phase,for which"three phases and three methods"has been proposed to prevent and treat RILI.For the early stage of RILI,that is intense heat toxin phase,it is recommended to use the method of clearing the lung and resolving toxins,usually with Yin Qiao Powder(银翘散)in modifications.Regarding the middle stage which is yin deficiency and heat accumulation phase,the method of enriching yin and venting heat is recommended,often using self-made Yangyin Qingfei Formula(养阴清肺方).In terms of the late stage,that is the static blood obstruction phase,It is recommended to invigorate blood and dissolve stasis,usually with self-made Qingfei Huoxue Formula(清肺活血方).