尊严疗法的心理干预在晚期肝癌靶向治疗患者中的应用

Application of psychological intervention based on dignity therapy in patients receiving targeted therapy for advanced liver cancer

目的:探讨基于尊严疗法的心理干预在晚期肝癌靶向治疗患者中的应用效果。方法:将2023年1月-2024年1月某院收治的120例晚期肝癌靶向治疗患者随机分为两组,对照组60例予以常规干预,观察组60例在其基础上予以基于尊严疗法的心理干预。比较两组服药依从性、尊严水平、自我感受负担和生命质量。结果:干预后,观察组服药依从性高于对照组(z=10.373,P<0.05);干预后,两组患者尊严量表(PDI)得分、自我感受负担量表(SPBS)中情感因素、经济因素、身体因素得分、癌症患者生命质量测定量表(QLQ-C30)中症状维度得分均降低,且观察组低于对照组(t=13.436,5.704,5.483,4.978,2.805;P<0.05);两组QLQ-C30中功能维度、总体健康得分均升高,且观察组高于对照组(t=3.815,2.202;P<0.05)。结论:尊严疗法的心理干预有助于改善晚期肝癌靶向治疗患者的尊严状况,提高患者的服药依从性和生命质量,降低自我感受负担。

Objective:To investigate the application effect of psychological intervention based on dignity therapy on patients with advanced liver cancer receiving targeted therapy.Methods:From January 2023 to January 2024,120 patients withtargeted therapy for advanced liver cancer in the hospital were randomized into two groups.Sixty cases in the control group were given routine intervention,and the other 60 cases in the observation group received psychological intervention based on dignity therapy on this basis.The medication compliance,dignity level,self-perceived burden and quality of life were compared between groups.Results:After intervention,the medication compliance in the observation group was higher than that in the control group(z=10.373,P<0.05).The score of Patient Dignity Inventory(PDI),scores of emotional factor,economic factor and physical factor of Self-Perceived Burden Scale(SPBS)and score of symptom dimension of Quality of Life Questionnaire for Cancer Patients(QLQ-C30)were decreased in both groups after intervention,and the above scores in the observation group were lower(t=13.436,5.704,5.483,4.978,2.805;P<0.05).The scores of functional dimension and overall health of QLQ-C30 in both groups were enhanced,and the scores were higher in the observation group(t=3.815,2.202;P<0.05).Conclusion:Psychological intervention based on dignity therapy is helpful to improve the dignity status of patients with advanced liver cancer undergoing targeted therapy,enhance the medication compliance and quality of life,and reduce the self-perceived burden.