地顶孢霉培养物对患输卵管炎蛋鸡产蛋性能的影响

Effects of Acremonium terricola culture on the laying performance of laying hens afflicted with oviduct inflammation

试验旨在研究地顶孢霉培养物对患输卵管炎的蛋鸡产蛋性能的影响,以期提高蛋鸡在产蛋后期的生产能力。试验将2棚390日龄、患输卵管炎的蛋鸡随机分为试验组和对照组,每组设4个重复,每个重复2 500只蛋鸡。对照组饲喂基础日粮,试验组饲喂添加1 g/kg地顶孢霉培养物的基础日粮。试验期21 d。结果显示:与对照组相比,试验组的产蛋率、哈夫单位、蛋重提高1.74%(P<0.05)、6.55%(P<0.05)、1.86%(P>0.05),死淘率、破蛋率和暗斑蛋率降低了34.29%(P<0.05)、76.00%(P<0.05)和35.80%(P<0.05)。与对照组相比,试验组蛋鸡血清炎症因子肿瘤坏死因子α (TNF-α)、白细胞介素-1β (IL-1β)、白细胞介素-6 (IL-6)、白细胞介素-12(IL-12)水平分别降低了23.76%(P<0.01)、6.02%(P<0.05)、16.49%(P<0.01)和19.18%(P<0.05),抗炎因子白细胞介素-4 (IL-4)、白细胞介素-10 (IL-10)水平分别提高了18.85%(P<0.05)和29.49%(P<0.01)。研究表明,饲料中添加1 g/kg地顶孢霉培养物可显著提高产蛋后期蛋鸡产蛋性能,其作用机制可能是地顶孢霉可作为抗炎剂降低产蛋后期蛋鸡输卵管炎症、肠道炎症等炎症的炎症因子表达,提高抗炎因子表达,减少机体炎症反应,从而达到提高产蛋率、改善蛋品质的效果。

The experiment aimed to investigate the impact of Acremonium terricola culture on the laying performance of hens with oviduct inflammation,in order to enhance the productivity of laying hens during the late laying period.A total of 390 hens at 90 days of age with oviduct inflammation were randomly divided into the experimental group and the control group,with four replicates per group,each consisting of 2500 laying hens.The control group was fed a basic diet,while the experimental group was fed the same diet supplemented with 1 g/kg of Acremonium terricola culture.The trial period was 21 days.The results showed that compared to the control group,the egg production rate,Haugh units,and egg weight in the experimental group increased by 1.74%(P<0.05),6.55%(P<0.05),and 1.86%(P>0.05),respectively,while the culling rate,broken egg rate,and spotted egg rate decreased by 34.29%(P<0.05),76.00%(P<0.05),and 35.80%(P<0.05),respectively.Compared to the control group,the levels of serum inflammatory factors such as tumor necrosis factorα(TNF-α),interleukin-1β(IL-1β),interleukin-6(IL-6),and interleukin-12(IL-12)in the experimental group laying hens were reduced by 23.76%(P<0.01),6.02%(P<0.05),16.49%(P<0.01),and 19.18%(P<0.05),respectively,while the levels of anti-inflammatory factors interleukin-4(IL-4)and interleukin-10(IL-10)were increased by 18.85%(P<0.05)and 29.49%(P<0.01),respectively.The study indicates that the addition of 1 g/kg Acremonium terricola culture in feed can significantly improve the laying performance of laying hens in the late laying period.The mechanism of action may involve the anti-inflammatory effects of Acremonium terricola,which can reduce the expression of inflammatory factors in the oviduct and intestinal inflammation of laying hens during the late laying period,increase the expression of anti-inflammatory factors,decrease systemic inflammatory responses,and thereby improve egg laying rate and egg quality.