两例人芽囊原虫感染病例报道及文献回顾

Two cases of Blastocystis hominis infection and literature review

目的对检验科日常工作中发现的2例疑似人芽囊原虫感染的异常大便标本进行分析与比对,为临床医生提供疾病诊断依据及协助制定诊疗方案。方法检验师通过肉眼观察大便标本性状、沃文特自动粪便处理系统(FA160)自动镜检、人工镜检、多人阅片等方法对2例疑似人芽囊原虫感染的异常大便标本进行分析。结果肉眼观察大便标本性状,发现其性状异常,通过FA160自动镜检可见异常有形成分。瑞氏染色后,通过精准的人工镜检、多人阅片,并与图谱进行比对,最终确定这2例患者为人芽囊原虫感染。结论这2例患者免疫系统均较弱,于住院期间出现了腹泻症状,且大便性状异常,经过检验师的分析,最终确认为人芽囊原虫感染。与临床沟通后,临床医生对这2例患者进行了甲硝唑口服治疗,此后2例患者复查大便常规后未见明显异常。患者的消化道症状得到了明显改善,生活质量得到了提高。

Objective Analyzing and comparing 2 abnormal fecal specimens suspected of Blastocystis hominis infection,which were identified during routine laboratory work,to provide clinicians with diagnostic evidence for the disease and assist in formulating diagnosis and treatment plans.Methods The laboratory physician analyzed 2 abnormal stool samples suspected of being infected with Blastocystis hominis by observing the characteristics of the stool specimens with the naked eye,using the WWT/FA160 for automatic microscopy,manual microscopy,and multi person reading.Results By visually observing the characteristics of the stool specimen,it was found that its characteristics were abnormal,and abnormal tangible components were visible through FA160 automatic microscopy.After Wright's staining,through precise manual microscopy,multi person review of the images,and comparison with the atlas,it was ultimately determined that these 2 patients were infected with Blastocystis hominis.Conclusion Both patients had weakened immune systems and experienced diarrhea during hospitalization,with abnormal stool characteristics noted.Through laboratory analysis,Blastocystis hominis infection was confirmed.After consultation with clinicians,both patients received oral metronidazole treatment.Subsequent stool routine tests showed no significant abnormalities.Digestive symptoms in the patients markedly improved,leading to an enhanced quality of life.