摘要
肝衰竭是临床一类急危重症肝病。骨髓间充质干细胞(BM-MSCs)具有向肝细胞分化、促进肝细胞再生,以及抑制肝细胞凋亡、坏死和炎性反应等作用,有助于修复受损的肝组织,改善肝功能,成为当前肝衰竭细胞治疗策略中极具应用潜力的一种新选择。
Liver failure is a kind of acute and severe liver disease.Bone marrow-derived mesenchymal stem cells(BM-MSCs)have the function of differentiating into hepatocytes.Promotion of the regeneration of hepatocytes regeneration,inhibition of apoptosis,necrosis and inflammation of hepatocytes,may facilitate repairing damaged liver tissue and improving liver function.BM-MSCs have become a new choice with great application potential in the treatment of liver failure.
作者
齐泽强
郭庭煜
吴治念
王亚东
QI Zeqiang;GUO Tingyu;WU Zhinian;WANG Yadong(Department of Infectious Disease,the Third Hospital of Hebei Medical University,Shijiazhuang 050051,China)
出处
《基础医学与临床》
CAS
2024年第11期1608-1612,共5页
Basic and Clinical Medicine
基金
河北省自然科学基金(H2023206042)
河北省政府临床医学优秀人才培养计划(ZF2023082)。
关键词
肝衰竭
间充质干细胞
再生
移植
liver failure
mesenchymal stem cell
regeneration
transplantation
