基于倾向匹配分析的孤立性肺结节危险因素研究

A study of risk factors for solitary pulmonary nodule based on propensity-matched analysis

目的基于倾向匹配分析孤立性肺结节危险因素。方法回顾性研究2021年1月~2023年8月新疆维吾尔自治区人民医院收治的156例肺结节患者,按照是否恶变,分为良性组58例、恶性组98例,收集所有患者临床和影像学资料。logistic回归分析孤立性肺结节危险因素。结果行倾向性评分匹配法,最终纳入100例进行logistic回归分析。匹配后多因素logistic回归分析发现,其中年龄、磨玻璃密度、分叶征、CEA水平及结节直径为恶性病变的独立危险因素(P<0.05)。结论年龄、血清CEA水平、磨玻璃密度、分叶征及结节直径为恶性肺结节的高危因素。

Objective Propensity-matched-based analysis of risk factors for solitary pulmonary nodules.Methods Retrospective study of 156 patients with lung nodules admitted to Xinjiang Uygur Autonomous Region People's Hospital from January 2021 to August 2023,divided into 58 cases of benign group and 98 cases of malignant group according to whether they were malignant or not.Clinical and imaging data of all the patients were collected.Logistic regression was used to analyze the risk factors of isolated lung nodules.Results A total of 100 patients were included,and the difference of each clinical characteristic between the two groups was not significant(P>0.05);matched multifactorial logistic regression analysis revealed,among others,that age,ground-glass density,pleural depression sign,lobulation sign,CEA level and nodule diameter were independent risk factors for malignant lesions.Conclusion Age,serum CEA level,ground glass density,lobar sign and nodule diameter are the risk factors for malignant pulmonary nodules.