中青年妇科癌症患者癌性厌食现状及其影响因素分析

Actualities of cancer-related anorexia and influencing factors in young and middle-aged patients with gynecological cancer

目的了解中青年妇科癌症患者癌性厌食发生现状及其影响因素,为临床干预提供依据。方法采用一般资料调查表、癌性厌食量表、化疗相关味觉改变量表(CITAS)、中文版失志量表(DS-MV)、家庭关怀指数问卷(APGAR)对269例中青年妇科癌症患者进行问卷调查。结果单因素分析显示,年龄越大患者癌性厌食量表评分越低,无固定陪护患者癌性厌食量表评分低于护工、家属或亲友陪护者(P<0.01)。中青年妇科患者癌性厌食量表评分与CITAS、DS-MV评分呈负相关(P<0.05),与APGAR评分呈正相关(P<0.05)。多元线性回归分析显示,年龄、主要照顾者及CITAS、DS-MV、APGAR评分为中青年妇科癌症患者癌性厌食的影响因素(P<0.05或0.01)。结论年龄、主要照顾者、化疗引起的味觉改变、失志水平、家庭功能是中青年妇科癌症患者癌性厌食的发生的影响因素。应尽早对患者进行相关评估,并进行积极干预,尽早改善癌症患者癌性厌食状况。

Objective To explore the actualities of cancer-related anorexia and influencing factors in young and middle-aged patients with gynecological cancer(GC).Methods Questionnaire surveys were conducted using general information questionnaire,Cancer Anorexia Scale(CAS),the Chemotherapyi nduced Taste Alteration Scale(CITAS),Demora lization Scle-mandarin version,(DS-MV),and Family Adaption,Partnership,Growth,Affection,and Resolve in 269 young and middle-aged GC patients.Results Single factor analysis showed that the older the patients were the lower the score on the CAS,the CAS scores were lower in patients without fixed caregiver than ones with caregivers of nursing assistant,family members or relatives and friends(P<0.01).The CAS scores of young and middle-aged GC patients were negatively related to the CITAS and DS-MV score(P<0.05)and positively to APGAR(P<0.05).Multiple linear regression analysis showed that age,main caregiver as well as CITAS,DS-MV and APGAR score were influencing factors of cancer-related anorexia in young and middle-aged GC patients(P<0.05 or 0.01).Conclusion Factors influencing the occurrence of cancerrelated anorexia are age,main caregiver,taste alteration induced by chemotherapy,demoralization level,and family function.Patients should be assessed as early as possible and actively intervened to improve cancer-related anorexia.