右侧阴囊丘疹性棘层松解角化不良1例

A case of papular acantholytic dyskeratosis of the right scrotum

报告右侧阴囊丘疹性棘层松解角化不良1例。患者男,58岁。因右侧阴囊丘疹伴瘙痒5年余就诊。皮肤科检查:右侧腹股沟及大腿根部大片密集或散在的粟粒至绿豆大小的丘疹,部分呈斑块状,表面轻微糜烂、浸渍、发白。皮损组织病理检查:角化过度,角化不全,表皮不规则增生,棘层松解,形成表皮内疱,可见较多角化不良细胞,真皮浅层淋巴细胞及浆细胞浸润。诊断:丘疹性棘层松解角化不良。予CO_(2)点阵激光治疗。2年后随访,患者皮疹反复发作,时轻时重。

To report a case of popular acantholytic dyskeratosis of the right scrotum.A 58-year-old man complained of pruritic papules on the right scrotum for over 5 years.Dermatologic examination revealed unevenly distributed,millet to green bean sized papules with erosion and maceration,on the right groin.Histopathological changes included hyperkeratosis,parakeratosis,irregular epidermal hyperplasia,acantholysis,intraepidermal vesicles,with a large number of dyskeratotic cells in addition to infiltration of lymphocytes and plasma cells in the dermis.Patient was diagnosed with papular acantholytic dyskeratosis and treated with fractional CO_(2)laser,and the rashes repeatedly relapsed when followed up 2 years later.