温针灸配合膀胱功能训练对肾气亏虚型缺血性脑卒中后尿潴留的影响

Curative Observation on Warming Needle Moxibustion Combined with Bladder Function Training in Treating Urinary Retention after Ischemic Stroke of Kidney Qi Deficiency Pattern

目的:探讨温针灸配合膀胱功能训练对肾气亏虚型缺血性脑卒中后尿潴留的影响。方法:将66例肾气亏虚型缺血性脑卒中后尿潴留患者按随机数字表法分为对照组和观察组各33例。对照组行膀胱功能训练,观察组在对照组基础上予温针灸干预;比较两组患者治疗前后尿流动力学参数、肾气亏虚证症状评分及血清内源性活性氧(reactive oxygen species,ROS)、丙二醛(malonaldehyde,MDA)、超氧化物歧化酶(superoxide dismutase,SOD)水平,观察两组临床疗效。结果:治疗后观察组患者最大尿流量、最大尿意时膀胱容量及血清SOD水平高于对照组(P<0.01),残余尿量、肾气亏虚证症状评分及血清ROS、MDA水平低于对照组(P<0.01);观察组总有效率为90.9%(30/33),高于对照组的66.7%(22/33)(P<0.05)。结论:温针灸配合膀胱功能训练治疗肾气亏虚型缺血性脑卒中后尿潴留疗效优于单纯膀胱功能训练,其机制可能与温针灸配合膀胱功能训练能够降低患者血清ROS、MDA表达,提高SOD表达有关。

Objective:To discuss the influence of warming needle moxibustion joined with bladder function training on urinary retention after ischemic stroke of kidney Qi deficiency pattern.Methods:Altogether 66 cases of urinary retention were allocated to the control group and the observation group according to random number table method with 33 cases in each group.The control group performed bladder function training,and the observation group accepted warming needle moxibustion based on the therapy the control group accepted.To compare the urodynamic parameters,symptom scores of kidney Qi deficiency pattern,and the levels of ROS,MDA and SOD before and after the treatment in the two groups,to observe clinical effects of the groups.Results:After the treatment,maximum urine flow,bladder capacity during a strong desire to void,the levels of serum SOD of the observation group were higher than these of the control group(P<0.01),residual urine volume,symptom scores of kidney Qi deficiency pattern,the levels of ROS and MDA were lower than these of the control group(P<0.01);total effective rate of the observation group was 90.9%(30/33),higher than 66.7%(22/33)of the control group(P<0.05).Conclusion:Warming needle moxibustion joined with bladder function training are superior to only bladder function training in the treatment of urinary retention after ischemic stroke of kidney Qi deficiency pattern,and its mechanism might be related to that the therapy could reduce the expressions of serum ROS and MDA,and increasethelevelsof SOD.