摘要
缓痛止泻软胶囊由白术、白芍、陈皮、防风共4味中药组成,具有疏肝补脾、缓痛止泻的功效,被广泛应用于腹泻型肠易激综合征的治疗。相关研究结果均表明,缓痛止泻软胶囊单用、联合其他中西药及非药物疗法均能改善腹泻型肠易激综合征的临床症状,并具有较好的临床疗效。为了更好地指导基层医师安全、有效应用缓痛止泻软胶囊,指导临床合理用药,由首都医科大学附属北京友谊医院联合中国医疗保健国际交流促进会中医药临床研究分会等相关领域专家,共同起草了《缓痛止泻软胶囊治疗腹泻型肠易激综合征基层用药专家共识》。该共识在临床专家的问卷调研和文献回顾的基础上,采用GRADE系统,充分结合专家经验,通过名义组法形成推荐意见或共识建议。该共识明确了缓痛止泻软胶囊治疗腹泻型肠易激综合征的适应证、证治要点、用法与用量、疗程、联合用药、安全性等,适用于各等级医院的中医师、西医师、全科医师和临床药师等。
Huantong Zhixie soft capsules,consisting of four kinds of traditional Chinese medicines:Atractylodes Macrocephala Koidz,Paeoniae Radix Alba,Citrus Reticulata and Saposhnikoviae Radix,possesses the effects of soothing the liver,nourishing the spleen,relieving pain,and stopping diarrhea.It is widely used in the treatment of diarrhea-predominant irritable bowel syndrome(IBS-D).Relevant studies showed that the clinical symptoms of IBS-D could be improved by using Huantong Zhixie soft capsules alone,combined with other Chinese and Western medicine and non-drug therapy,and the efficacy was significant.In order to better guide the safe and effective use of Huantong Zhixie soft capsules for primary physicians and guide the rational use of clinical drugs,Expert Consensus on Huantong Zhixie Soft Capsules in the Treatment of Diarrhoeal-predominant irritable bowel syndrome in Primary Care was jointly drafted by relevant experts in related fields from Beijing Friendship Hospital,Capital Medical University and Clinical Research on Traditional Chinese Medicine Branch of China International Exchange and Promotive Association for Medical and Health Care.Based on the questionnaire survey and literature review of clinical experts,the consensus adopts the GRADE system and fully combined with expert experience to form recommendations or consensus recommendations through the Nominal Group Technique.This consensus clarifies the indications,key points of diagnosis and treatment,usage and dosage,course of treatment,drug combination,and safety of Huantong Zhixie soft capsules in the treatment of IBS-D,which is suitable for Chinese clinicians,Western clinicians,general clinicians and clinical pharmacists in hospitals of various levels.
作者
陈熹
谢俊大
陈佳帅
王堃
来要良
马致洁
CHEN Xi;XIE Junda;CHEN Jiashuai;WANG Kun;LAI Yaoliang;MA Zhijie(Dept.of Pharmacy,Beijing Friendship Hospital,Capital Medical University,Beijing 100053,China;Clinical Research on Traditional Chinese Medicine Branch of China International Exchange and Promotive Association for Medical and Health Care,Beijing 100009,China;Dept.of Pharmacy,Beijing Miyun Hospital of Traditional Chinese Medicine,Beijing 101599,China;Dept.of Pharmacy,Beijing University of Chinese Medicine Third Affiliated Hospital,Beijing 100029,China;Dept.of Spleen and Stomach Diseases,Beijing Xuanwu Traditional Chinese Medicine Hospital,Beijing 100050,China)
出处
《中国医院用药评价与分析》
2024年第10期1167-1170,共4页
Evaluation and Analysis of Drug-use in Hospitals of China
基金
国家重点研发计划资助项目(No.2023YFC2308200)。
关键词
缓痛止泻软胶囊
湿气
腹泻型肠易激综合征
专家共识
Huantong Zhixie soft capsules
Dampness
Diarrhea-predominant irritable bowel syndrome
Expert consensus