基于拟合光源的荧光摄像系统性能测试与评价方法

Performance Evaluation Methods Based on Spectral Fitting for Near-Infrared Fluorescence Imaging

基于吲哚菁绿造影剂的荧光摄像系统在手术和研究中快速普及,但目前荧光性能的检测方法存在复现与溯源的问题,无法满足标准化评价荧光摄像系统的新需求。该研究提出基于拟合光源的荧光性能评价方法,定义三类荧光性能参数并通过对比验证。基于拟合光源的荧光性能评价方法为建立荧光图像质量评估标准提供可行的标准参考。

The use of near-infrared fluorescence imaging with indocyanine green in surgery and research is becoming increasingly widespread.Nowadays,the performance test methods for near-infrared fluorescence imaging have the problems of bad repeatability and untraceability.In order to address the emerging need for standardization of near-infrared fluorescence imaging systems,it is necessary to identify the best methods suitable for objective,quantitative testing of image quality characteristics.Based on fluorescence imaging literature,we have developed and demonstrated three test methods for evaluation of fluorescence image quality,which are based upon simulation of near-infrared fluorescence.These methods have the potential to facilitate other quantitative comparison of device performance,with the long-term goal of establishing standards for fluorescence image quality assessment.