简易模体和标准模体检测SPECT系统性能的对比研究

Comparative Study on SPECT System Performance Parameters Measured by Simple and Standard Modules

目的使用自制简易模体和标准模体分别对单光子发射型计算机断层显像仪(Single-Photon Emission Computed Tomography,SPECT)设备的系统性能指标系统空间分辨力和系统平面灵敏度进行检测,分析2种模体检测结果的差异,评价简易模体应用于SPECT系统性能评估的可行性。方法采用GE Discovery NM/CT 670 Pro显像系统,参考国家标准WS 523-2019和美国电器制造商协会(NEMA)标准NU-1-2012,根据测量要求,采用标准模体和自制简易模体分别制备99mTc平面源和双线源,在标准检测条件下使用2种模体测量系统平面灵敏度和系统空间分辨力,并记录测量结果。改变源到探头的距离,其他采集条件不变,在不同源距下分别采用标准模体和简易模体进行检测,分析2种模体测得数据的差异性和一致性。结果在标准检测条件下,使用简易双线源模体和标准双线源模体测得系统空间分辨力差异无统计学意义(探头1:Z=-1.184,P=0.854>0.05,探头2:Z<0.001,P=1.000>0.05);使用简易平面源模体和标准平面源模体测得系统平面灵敏度差异无统计学意义(探头1:Z=-1.826,P=0.068>0.05,探头2:Z=-1.841,P=0.066>0.05)。在不同源距下分别用简易模体和标准模体进行系统性能指标检测,2种模体测得组间系统空间分辨力(Z=-1.460,P=0.144>0.05)和系统平面灵敏度(Z=-1.830,P=0.068>0.05)差异均无统计学意义。Bland-Altman分析结果显示,简易模体和标准模体测得系统空间分辨力(差值95%CI:-1.036~2.186)和系统平面灵敏度(差值95%CI:0.842~12.158)一致性均良好。结论采用自制简易模体可在核医学科基础条件下实现SPECT系统空间分辨力和系统平面灵敏度的自主检测,为设备系统性能的快速评估提供了有效替代方案。

Objective To test the system spatial resolution and system plane sensitivity of single-photon emission computed tomography(SPECT)equipment by self-made simple module and standard module,so as to analyze the difference of detection results between the two modules to evaluate the feasibility of simple module applied to SPECT system performance evaluation.Methods GE Discovery NM/CT 670 Pro imaging system was used,and according to the national standard WS 523-2019 and the National Electrical Appliance Manufacturers Association(NEMA)standard NU-1-2012,99mTc planar source and dual-wire source were prepared by standard module and self-made simple module,respectively.The system plane sensitivity and system spatial resolution were measured by using the two modules under the standard detection conditions,and the measurement results were recorded.The distance from the source to the probe was changed,and other acquisition conditions remained unchanged,the standard and simple models were respectively used for detection under different source distances,and the difference and consistency of the measured data between the two models were analyzed.Results Under standard detection conditions,there was no significant difference in system spatial resolution between simple and standard dual-wire source modules(probe 1:Z=-1.184,P=0.854>0.05,probe 2:Z<0.001,P=1.000>0.05).There was no significant difference in the system plane sensitivity measured by simple and standard planar source modules(probe 1:Z=-1.826,P=0.068>0.05,probe 2:Z=-1.841,P=0.066>0.05).There was no significant difference in system spatial resolution(Z=-1.460,P=0.144>0.05)and system plane sensitivity(Z=-1.830,P=0.068>0.05)between the two groups measured by two different modules when the acquisition conditions were changed.Bland-Altman analysis showed that the system spatial resolution(difference 95%CI:-1.036~2.186)and the system plane sensitivity(difference 95%CI:0.842~12.158)of the two models were both in good agreement.Conclusion The self-determination of SPECT system spatial resolution and system plane sensitivity can be realized under the basic condition of nuclear medicine,which provides an effective alternative for the rapid evaluation of equipment system performance.