原位电离质谱技术在中药质量控制中的研究进展

Research Progress of Ambient Ionization Mass Spectrometry in Quality Control of Chinese Herbal Medicine

中药化学成分在中药质量控制中发挥着极其重要的作用,传统分析方法处理样品过程繁琐且耗时长,原位电离质谱技术(AIMS)具有快速、原位、无损等特点,能实现中药样品中多种化学成分的同时测定,目前已应用于中药质量控制,具有广阔的发展前景。本文归纳并梳理了AIMS离子化技术的分类、工作原理和检测特点及其在中药质量控制中的研究现状,并展望了该技术的未来发展方向和应用前景。

In-depth research and interpretation of the chemical components of Chinese Herbal Medicine play a crucial role in its quality control.Traditional analytical methods for processing samples are cumbersome and time-consuming.Ambient Ionization Mass Spectrometry(AIMS)offers rapid,in-situ,and non-destructive analysis,enabling the simultaneous determination of multiple chemical components in TCM samples.Currently,AIMS has been applied to Chinese herbal medicine quality control and shows great potential for future development.This paper summarizes the classification,working principles,and detection characteristics of AIMS ionization technologies and reviews the current research status of AIMS in Chinese herbal medicine quality control.Additionally,it discusses the future development directions and application prospects of this technology.