EMR与电凝电切术式治疗胃肠道息肉的效果及对机体炎症的影响分析

Effect of EMR and Electrocoagulation in the Treatment of Gastrointestinal Polyps and its Influence on Inflammation

目的研讨内镜下黏膜切除术式(endoscopic mucosal resection,EMR)与内镜下电凝电切术式治疗胃肠道息肉的效果及对机体炎症的影响。方法随机选取2023年2月—2024年2月福建省福清市医院收治的100例胃肠道息肉患者为研究对象,依据不同手术方法分为对照组和观察组,各50例。对照组行内镜下电凝电切术式,观察组行EMR术式,比较两组患者的手术疗效、围术期基础指标水平、机体炎症指标水平以及手术并发症发生情况。结果观察组手术治疗总有效率94.00%(47/50)高于对照组的80.00%(40/50),差异有统计学意义(χ^(2)=4.332,P=0.037)。观察组手术时间、术中出血量、术后胃肠功能恢复时间、住院时间均优于对照组,差异有统计学意义(P均<0.05)。术后1 d,观察组降钙素原水平、白细胞介素-17水平和白细胞介素-6水平均低于对照组,差异有统计学意义(P均<0.05)。观察组并发症总发生率低于对照组,差异有统计学意义(P<0.05)。结论相较于内镜下电凝电切术式,EMR用于胃肠道息肉患者可提高临床疗效,降低患者机体炎症水平,安全性更佳。

Objective To investigate the effect of endoscopic mucosal resection(EMR)and endoscopic electrocoagula⁃tion in the treatment of gastrointestinal polyps and its effect on inflammation.Methods A total of 100 patients with gastrointestinal polyps admitted to Fujian Fuqing City Hospital from February 2023 to February 2024 were randomly selected as the study objects and divided into control group and observation group according to different surgical meth⁃ods,50 cases in each group.The control group underwent endoscopic electrocoagulation,and the observation group underwent EMR.The surgical efficacy,perioperative basic index level,body inflammation index level and surgical complications were compared between the two groups.Results The total effective rate of surgical treatment in the ob⁃servation group was 94.00%(47/50)higher than that in the control group 80.00%(40/50),and the difference was sta⁃tistically significant(χ^(2)=4.332,P=0.037).The operation time,intraoperative blood loss,postoperative gastrointestinal function recovery time and hospitalization time of the observation group were better than those of the control group,and the differences were statistically significant(all P<0.05).One day after operation,the levels of procalcitonin,interleu⁃kin-17 and interleukin-6 in the observation group were lower than those in the control group,and the differences were statistically significant(all P<0.05).The total incidence of complications in the observation group was lower than that in the control group,the difference was statistically significant(P<0.05).Conclusion Compared with endoscopic electroco⁃agulation,EMR can improve the clinical efficacy,reduce the level of inflammation in patients with gastrointestinal pol⁃yps,and has better safety.