新疆地区哈萨克族类风湿关节炎的临床特点

Clinical Characteristics of Rheumatoid Arthritis in Kazakh Ethnic Group in Xinjiang Region

目的探究新疆地区哈萨克族类风湿关节炎的临床特点。方法择取本院80例类风湿关节炎患者(2023年1月至2024年1月)深入分析,依据起病年龄分组(老年组27例、中年组29例、青年组24例),分析其临床特点。结果三组肿胀关节数、压痛关节数、关节炎疾病活动评分(DAS28)等临床特征对比差异均无统计学意义(均P>0.05);三组起病方式与首发关节对比差异有统计学意义(均P<0.05)。三组C反应蛋白(CRP)、低密度脂蛋白(LDL)指标水平对比差异无统计学意义(均P>0.05);老年组红细胞沉降率(ESR)、类风湿因子(RF)指标水平高于青、中年组,青年组白蛋白(ALB)指标水平高于老年组(均P<0.05)。三组并发症发生率对比差异无统计学意义(P>0.05)。结论不同年龄段类风湿关节炎并发症无统计学意义,但老年患者偏高,临床特征较为相似;起病方式以急性方式为主,且老年患者居多,中年患者相对较多,其次为老年患者、青年患者。临床需采用有效的早期干预措施,中青年患者需避免对关节造成破坏,老年患者应避免关节功能丧失。

Objective Exploring the clinical characteristics of rheumatoid arthritis in the Kazakh ethnic group in Xinjiang region.Methods Select 80 patients with rheumatoid arthritis(January 2023 to January 2024)from our hospital for in-depth analysis,and group them according to their onset age(27 in the elderly group,29 in the middle-aged group,and 24 in the young group)to analyze their clinical characteristics.Results There was no statistically significant difference in the comparison of clinical characteristics such as the number of swollen joints,the number of painful joints,and the arthritis disease activity score(DAS28)among the three groups(all P>0.05);there was a difference in the comparison of the mode of onset of disease and the first joints among the three groups(all P<0.05).There was no difference in the comparison of the levels of C-reactive protein(CRP)and low-density lipoprotein(LDL)indicators among the three groups(all P>0.05);the levels of erythrocyte sedimentation rate(ESR)and rheumatoid factor(RF)indicators in the elderly group were higher than those in the young and middle-aged groups,and the level of albumin(ALB)indicators in the youth group was higher than those in the elderly group(all P<0.05).There was no difference in the comparison of complication rates among the three groups(P>0.05).Conclusions There was no statistically significant difference in the incidence of rheumatoid arthritis complications among different age groups,but the incidence was higher in elderly patients with similar clinical characteristics;The onset mode is mainly acute,with elderly patients being the majority,middle-aged patients being relatively more common,followed by elderly and young patients.Effective early intervention measures should be adopted in clinical practice,and middle-aged and young patients should avoid causing damage to joints,while elderly patients should avoid joint function loss.