血府逐瘀汤结合硝酸甘油片用于冠心病心绞痛对患者疼痛程度及治疗有效率的影响

Effect of Xuefu Zhuyu Decoction Combined with Nitroglycerin Tablet on Pain Degree and Treatment Efficiency of Patients with Angina Pectoris of Coronary Heart Disease

目的探讨血府逐瘀汤结合硝酸甘油片用于冠心病心绞痛对患者疼痛程度及治疗有效率的影响。方法选取2023年1月至2024年1月我院收治的冠心病心绞痛82例,根据治疗方式不同分为两组,对照组选择硝酸甘油片治疗,研究组在此基础上配合血府逐瘀汤进行治疗,比较两组的临床治疗效果、不良反应率、炎症因子及血脂水平、视觉模拟量表(VAS)及生活质量(SF-36)评分。结果研究组治疗有效率、SF-36评分高于对照组,不良反应发生率、VAS评分低于对照组(均P<0.05)。治疗后,研究组白细胞介素6(IL-6)、超敏C反应蛋白(hs-CRP)、血清总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)等指标水平均低于对照组(均P<0.05)。结论血府逐瘀汤结合硝酸甘油片用于冠心病心绞痛的效果显著,可以有效改善机体的疼痛程度和血脂水平,减少不良反应,调节炎症指标,提高生活质量。

Objective To investigate the effect of Xuefu Zhuyu Decoction combined with nitroglycerin tablet on the pain degree and treatment efficiency of patients with angina pectoris of coronary heart disease.Methods A total of 82 patients with angina pectoris of coronary heart disease treated in our hospital from January 2023 to January 2024 were divided into two groups according to different treatment methods.The control group was treated with nitroglycerin tablets,and the study group was treated with Xuefu Zhuyu Decoction on this basis.The clinical therapeutic effect,adverse reaction rate,inflammatory factors,blood lipid levels,VAS and quality of life scores of the two groups were compared.Results The treatment efficiency and SF-36 score of the study group were higher than those of the control group,and the incidence of adverse reactions and VAS score were lower than those of the control group(all P<0.05).After treatment,the levels of interleukin-6(IL-6),high-sensitivity C-reactive protein(hs-CRP),serum total cholesterol(TC),triglyceride(TG),and low-density lipoprotein cholesterol(LDL-C)were lower in the study group than in the control group(all P<0.05).Conclusions Xuefu Zhuyu Decoction combined with nitroglycerin tablet can effectively improve the pain degree and blood lipid level of the body,reduce adverse reactions,regulate inflammatory indicators,improve the quality of life.