临床科研数据平台的建设与应用

Construction and application of clinical research data platform

目的:探索临床科研数据平台的建设和应用。方法:以中国科学技术大学附属第一医院(安徽省立医院)为例,构建临床科研数据平台技术架构,建立操作型数据存储、临床数据中心、科研数据中心和专病数据库4层数据体系,采集和整合医院信息系统数据,进行数据质量控制、数据标签化与数据安全管理,以建立可支持临床研究的高质量数据平台。结果:临床科研数据平台实现了医学数据检索、专科专病管理与数据分析等自主化、流程化的临床科研服务。结论:临床科研数据平台沉淀数据资产,可满足医学研究的数据使用需求,从而促进数据从被动支撑向主动引智的转变,激发数据生产力。

Objective To explore the construction and application of clinical research data platforms.Methods Taking the First Hospital affiliated to University of Science and Technology of China(Anhui Provincial Hospital)as an example,a technical framework of clinical research data platform was constructed,a four-tier data system of operational data storage,clinical data center,research data center,and specialized disease database was established.Data collection and integration of hospital information system were carried out,and data quality control,data labeling,and data security management were carried out to establish a high-quality data platform that can support clinical research.Results The clinical research data platform achieved independent and streamlined clinical research services such as medical data retrieval,specialized disease management and data analysis.Conclusion Clinical research data platform can deposit data assets,meet the data usage needs of medical research,so as to promote the transformation of data from passive support to active intelligence,and stimulate data productivity.