儿童难治型支原体肺炎早期预测指标研究

Study on early predictors of refractory mycoplasma pneumonia in children

目的:探讨儿童难治型支原体肺炎(RMPP)与普通型支原体肺炎(MPP)的C反应蛋白(CRP)、中性粒细胞比例(NEU%)、D-二聚体以及肝功能指标之间的差异从而给临床提供参考价值。方法:回顾性分析医院收治的90例支原体肺炎患者,其中诊断为RMPP的患儿设为观察组(30例),选取同时期入院的MPP患儿作为对照组(60例),分析比较两组儿童在入院后CRP、NEU(%)、D-二聚体以及肝功能指标之间的差异。结果:观察组患儿的CRP、NEU(%)以及D-二聚体显著高于对照组(P<0.05),同时还发现观察组患儿的血清谷丙转氨酶(ALT)和谷氨酰转移酶(GGT)高于对照组(P<0.05)。结论:难治型支原体肺炎CRP、NEU(%)、ALT和GGT比普通型支原体肺炎患者明显升高,更容易发生肝损伤。

Objective:Study of Refractory mycoplasma pneumoniae pneumonia and Mycoplasma pneumoniae pneumonia C-reactive protein,neutrophil ratio,D-dimer,and liver function indicators were different to provide clinical reference value.Method:A A retrospective analysis was performed on 90 patients with mycoplasma pneumonia admitted to hospital.The children diagnosed with RMPP were set as the observation group(n=30),and MPP children admitted during the same period were selected as the control group(n=60).The differences of CRP,NEU(%),D-dimer and liver function indexes were analyzed and compared between the two groups after admission.Results:CRP,NEU(%)and D-dimer in observation group were significantly higher than those in control group(P<0.05),serum alanine aminotransferase(ALT)and glutamyltransferase(GGT)in observation group were higher than those in control group(P<0.05).Conclusion:CRP,NEU(%),ALT and GGT in patients with refractory mycoplasma pneumonia are significantly higher than those with common mycoplasma pneumonia,and liver injury is more likely to occur.