TyG指数与非糖尿病患者心房颤动射频消融术后1年内复发的相关性研究

Correlation study of TyG index and recurrence of atrial fibrillation within 1 year after radiofrequency ablation in non-diabetic patients

目的:探讨甘油三酯葡萄糖(TyG)指数与射频消融术后心房颤动(房颤)1年内复发之间的关联。方法:回顾性选取200例首次行射频消融术的房颤患者,收集患者的临床资料和术后12个月的随访数据,观察患者是否出现房颤复发,依据随访结果将患者分为复发组和未复发组。比较两组TyG指数的差异,分析影响房颤复发的危险因素及独立预测因子。结果:相较于非复发组,房颤复发组患者的TyG指数明显升高(8.70±0.06 vs 8.48±0.04,P<0.05)。多因素回归分析显示,TyG指数是射频消融术后房颤复发的独立危险因素。受试者工作特征曲线示房颤复发TyG指数曲线下面积为0.627(95%CI0.541~0.714,P<0.05),预测房颤复发的截断值为8.59。结论:术前高水平TyG指数提示房颤患者射频消融术后具有较高的复发风险。

Objective This study investigated the association between triglyceride glucose(TyG)index and the recurrence of atrial fibrillation(AF)within 1 year after radiofrequency ablation.Methods The 200 patients with AF who underwent radiofrequency ablation for the first time were retrospectively selected.Clinical data and follow-up data after surgery 12 months were collected.According to the follow-up results,patients were divided into recurrence group and non-recurrence group.The difference of TyG index between the two groups was compared.Results Compared with the non-recurrent group,the TyG index in the recurrent group was significantly increased(8.70±0.06 vs 8.48±0.04,P<0.05).Multivariate regression analysis showed that TyG index was an independent risk factor for recurrent AF after radiofrequency ablation.The area under curve of TyG index was 0.627(95%CI 0.541-0.714,P<0.05),and the best cut-off value of TyG index in predicting AF recurrence was 8.59.Conclusion High TyG index indicates that patients with AF have a higher risk of recurrence after radiofrequency ablation.