真实世界维生素注射剂用药模式分析

Real-world data on medications with vitamin injections

目的对住院期间使用维生素注射剂的患者进行分析,为临床用药模式和药品使用监测提供参考。方法数据来源于10家三级甲等医院,选取2020年1月1日至2022年12月31日入院接受过维生素注射剂治疗的住院患者为研究对象,收集患者的基线信息、科室、诊断、用药情况等。应用MySQL 5.7和Stata 17软件进行数据治理和统计分析,计数资料采用例数和构成比进行统计学描述;计量资料以均数±标准差(x±s)、中位数和四分位数[M(P_(25),P_(75))]进行表示。结果共31307人次接受维生素注射剂,其中17860人次(57.05%)为男性,60岁以上老年人占比52.23%,医疗付费方式以医疗保险付费为主(92.51%)。使用人次前5位的临床科室为普通外科(23.43%)、重症医学科(9.90%)、肛肠科(8.15%)、肿瘤科(7.75%)、泌尿外科(7.52%)。使用人次占前5位的疾病分别是肺炎(病原体未特指)(5.14%)、胃恶性肿瘤(4.64%)、其他医疗照顾(3.72%)、结肠恶性肿瘤(3.56%)、部位未特指的恶性肿瘤(3.40%)。氯化钾(4.48%)、胰岛素(2.40%)、人血白蛋白(1.43%)、呋塞米(1.09%)、葡萄糖酸钙(1.08%)、肝素(1.04%)、复方氨基酸(18AA-Ⅱ)(1.00%)为使用频率较高的合并用药。结论真实世界数据显示,在使用维生素注射剂的患者中,普通外科患者最多,肺炎(病原体未特指)患者最多。通过对维生素注射剂用药模式分析,明确特征类型患者,指导临床用药,使更多患者获益。

Objective To analyze the usage of vitamin injections among inpatients so as to provide references for clinical medications and monitoring of drug use.Methods The data was collected from 10 A-class hospitals.Inpatients who had been treated with vitamin injections between 2020 and 2022 were selected as the subjects.The baseline information of the patients,departments,diagnosis,and medications was collected.MySQL 5.7 and Stata 17 software were used for data governance and statistical analysis.The counting data was statistically described by the number of cases and composition ratio.Results Vitamin injections were used 31307 times,17860 of which involved males(57.05%).The percentage of people over 60 years old was 52.23%.Most of the patients paid via medical insurance(92.51%).The top five departments in terms of usage were the Department of General Surgery(23.43%),Department of Intensive Care Medicine(9.90%),Anorectal Department(8.15%),Department of Oncology(7.75%),and Department of Urology(7.52%).The top five diseases involved were pneumonia(the pathogens not specified)(5.14%),gastric malignant tumor(4.64%),other medical care(3.72%),colon malignant tumor(3.56%),malignant tumor in unspecified locations(3.40%).Potassium chloride(4.48%),insulin(2.40%),human albumin(1.43%),furosemide(1.09%),calcium gluconate(1.08%),heparin(1.04%),compound amino acids(18AA-II)(1.00%)were the combined medications most frequently used.Conclusion The real-world data suggests that the usage of vitamin injections is the highest among patients under general surgery,and among patients with pneumonia(pathogens not specified).The analysis of medications with vitamin injections has revealed the characteristics of patients involved,which can benefit medications and patients.