猫胱氨酸结石的病例报告

Case Report of Feline Cystine Urolithiasis

1只2岁的暹罗猫因排尿困难来本院就诊,通过实验室检查和影像学检查确诊为胱氨酸尿症和尿石症,手术治疗后进一步确诊为胱氨酸结石同时存在下泌尿道感染,基因检测确认患猫存在胱氨酸尿症突变基因。患猫于术后对症治疗和饮食管理后仍出现结石复发,加入硫普罗宁药物治疗后,下泌尿道症状得到明显控制。本病例提示猫的胱氨酸尿症和胱氨酸结石治疗需多手段结合,通常预后良好。

A 2-year-old Siamese cat presented to our clinic with difficulty urinating.Laboratory and imaging examinations diagnosed cystinuria and urolithiasis.Surgical treatment further confirmed the presence of cystine stones and a concurrent lower urinary tract infection.Genetic testing identified a mutation associated with cystinuria in the affected cat.Despite symptomatic treatment and dietary management post-surgery,the cat experienced stone recurrence.The addition of tiopronin treatment significantly controlled the lower urinary tract symptoms.This case suggests that treating cystinuria and cystine stones in cats requires a multi-faceted approach,generally leading to a favorable prognosis.