对比化学发光法与酶联免疫吸附试验在乙肝两对半中的检测价值

To Compare the Value of Chemiluminescence and Enzyme-linked Immunosorbent Assay in the Detection of Viral Hepatitis Type B

文章分析了乙肝两对半检验所采用的化学发光法与酶联吸附法的应用价值。共对100例乙肝患者展开了研究,采用化学发光法、酶联免疫吸附法进行检测,以观察患者的检查结果。在乙肝两对半检测中,化学发光法的检出结果更高(P<0.05)。同时,两种检查方法的血清标志物检测结果相差不大(P>0.05),且化学发光法的检出率高于酶联免疫吸附测定法。结果表明,化学发光法的敏感性和特异性更强,能够检测到较低浓度的乙肝病毒标志物,在早期乙肝感染的筛查和诊断中更具优势;而酶联免疫吸附试验则更适用于抗体检测,能够判断患者是否曾经感染过乙肝病毒。因此,对于乙肝两对半的检测,以化学发光法作为首选方法,同时结合酶联免疫吸附试验来全面评估患者的感染状态。

The paper analyzed the application value of chemiluminescence and enzyme-linked immunosorbent assay in the detection of viral hepatitis type B.A total of 100 patients with viral hepatitis type B participated in the study,all of which were detected by chemiluminescence and enzyme-linked immunosorbent assay,so as to observe the detection results of the patients.The results of chemiluminescence were higher in the detection of viral hepatitis type B(P<0.05).In addition,there was little difference between the two methods in the detection of serum markers(P>0.05),and the detection rate of chemiluminescence was higher than that of enzyme-linked immunosorbent assay.It indicated that chemiluminescence had higher sensitivity and specificity,and can detect lower concentrations of HBV markers,so it had more advantages in the early screening and diagnosis of viral hepatitis type B.Enzyme-linked immunosorbent assay was more suitable for detecting antibodies,which can determine whether patients have been infected with hepatitis B virus.Therefore,for the detection of viral hepatitis type B,chemiluminescence can be used as the preferred method,and enzyme-linked immunosorbent assay can be combined to comprehensively evaluate the infection status of patients.