高脂血症对脏器缺血再灌注损伤的影响及其药物防治进展

Research Progress on the Effects of Hyperlipidemia on Organ Ischemia-reperfusion Injury and Drug Treatment

高脂血症是一种代谢紊乱性疾病,累及多器官组织,是脏器缺血/再灌注损伤的重要危险因素,其机制涉及氧化应激、无菌性炎症和无复流等。本文着重阐述高脂血症对脏器缺血/再灌注损伤的影响及其药物防治,为相关疾病的防治提供参考。

Hyperlipidemia is a metabolic disorder disease that involves multiple organs and tissues and is an important risk factor for organ ischemia/reperfusion injury.Its mechanism involves oxidative stress,aseptic inflammation and no-reflow.This article focuses on elaborating the impact of hyperlipidemia on organ ischemia/reperfusion injury and its drug prevention and treatment,in order to provide a reference for the prevention and treatment of related diseases.