2013—2022年汉中市老年人HIV筛查有反应样本确证结果分析

Analysis of confirmatory results of HIV screening reactive samples among the elderly in Hanzhong City from 2013 to 2022

目的对汉中市老年人HIV筛查有反应样本的确证试验结果进行分析,为艾滋病的防治工作提供依据。方法对2013—2022年汉中市筛查实验室来源的557份HIV筛查有反应血液样本采用免疫印迹试验进行确证试验,采用SPSS 20.0软件进行结果的统计分析,利用χ^(2)检验进行组间比较。结果HIV筛查有反应样本确证试验阳性人群以男性、50~<60岁、已婚、农民(工)及中学和中专文化为主。不同性别、婚姻状况、送检机构的HIV筛查有反应样本,确证试验阳性率差异有统计学意义(χ^(2)=9.552、9.120、17.859,P<0.05)。汉台区、勉县HIV筛查有反应样本较多,不同县区HIV筛查有反应样本确证试验阳性率差异有统计学意义(χ^(2)=31.991,P<0.05)。自愿咨询和配偶阳性人群的确证试验阳性率最高,不同人群确证试验阳性率差异有统计学意义(χ^(2)=37.775,P<0.05)。ELISA法的确证试验阳性率最高为87.45%,化学发光法为56.45%。不同筛查方法确证试验阳性率差异有统计学意义(χ^(2)=52.036,P<0.05)。结论汉中市老年人HIV筛查有反应样本占比上升,确证试验阳性率高,需采取针对性的措施,优化艾滋病预防宣传方式,扩大检测覆盖面,关心老年人的身心健康,以减少艾滋病在老年人中的传播。

Objective To analyze the confirmatory test results of HIV screening reactive samples in the elderly in Hanzhong City,and to provide evidence for the prevention and treatment of AIDS.Methods A total of 557 HIV screening reactive blood samples from screening laboratories in Hanzhong City from 2013 to 2022 were conducted confirmatory tests using immunoblot assay.SPSS 20.0 software was used for statistical analysis of the results,and theχ^(2)test was used for comparison between groups.Results Positive population for the confirmatory test of HIV screening reactive samples were people with predominantly male,50-<60 years old,married,farmers(laborers),and middle school and secondary technical school culture.There were statistically significant differences in positive rates of confirmatory test for HIV screening reactive samples among different gender,marital status,and inspection institutions(χ^(2)=9.552,9.120,17.859,P<0.05).There were more HIV screening reactive samples in Hantai District and Mianxian County,and the difference in the positive rate of confirmatory tests for HIV screening reactive samples in different districts and counties was statistically significant(χ^(2)=31.991,P<0.05).The positive rate of confirmatory test of voluntary counseling and positive spouses population was the highest,and the difference in the positive rate of confirmatory test among different populations was statistically significant(χ^(2)=37.775,P<0.05).The highest positive rate of confirmatory test was 87.45%for ELISA and 56.45%for chemiluminescence.There was a statistically significant difference in the positive rate of confirmatory test between different screening methods(χ^(2)=52.036,P<0.05).Conclusion The proportion of reactive samples for HIV screening reactive samples among the elderly in Hanzhong City has increased,and the positive rate of confirmatory test is high.Targeted measures should be taken to optimize the way of AIDS prevention propaganda,expand the coverage of testing,and care for the physical and mental health of the elderly in order to reduce the spread of AIDS among the elderly.