柴胡加龙骨牡蛎汤联合佐匹克隆片对缺血性脑卒中后失眠患者神经功能及睡眠质量的影响

Effect of Chaihu Plus Longgu Muli Decoction Combined with Zopiclone Tablets on Neurological Function and Sleep Quality in Patients with Insomnia after Ischemic Stroke

目的分析柴胡加龙骨牡蛎汤联合佐匹克隆片治疗缺血性脑卒中后失眠的疗效。方法选取2022年8月—2023年7月济南市章丘区中医医院收治的120例缺血性脑卒中后失眠患者为研究对象,按照治疗方法的不同分为两组,各60例。对照组采用佐匹克隆片治疗,观察组在对照组治疗的基础上联合柴胡加龙骨牡蛎汤治疗。对比两组中医证候积分、神经功能、失眠程度及睡眠质量评分。结果观察组夜寐不安评分、神疲乏力评分、寐后易惊评分、头目昏沉评分、神经功能评分、失眠程度评分均低于对照组,差异有统计学意义(P均<0.05)。观察组睡眠质量评分为(7.65±1.78)分,低于对照组的(11.34±1.86)分,差异有统计学意义(t=11.102,P<0.05)。结论柴胡加龙骨牡蛎汤联合佐匹克隆片可显著提高缺血性脑卒中患者睡眠质量和神经功能。

Objective To analyze the curative effect of Chaihu plus Longgu Muli Decoction combined with zopiclone tablets on insomnia after ischemic stroke.Methods A total of 120 patients with insomnia after ischemic stroke who were admitted to Jinan Zhangqiu District Hospital of Traditional Chinese Medicine from August 2022 to July 2023 were selected as the research objects.According to the different treatment methods,they were divided into two groups,with 60 cases in each group.Control group treated with zopiclone tablets,on the basis of the observation group was treated in the control group with Chaihu Plus Longyu Muli Decoction.The traditional Chinese medicine syndrome scores,neurological function,insomnia degree and sleep quality scores were compared between the two groups.Results The scores of night sleep disturbance,mental fatigue,post-sleep fright,dizziness,neurological function and insomnia in the observation group were lower than those in the control group,and the differences were statistically significant(all P<0.05).The sleep quality score of the observation group was(7.65±1.78)points,which was lower than(11.34±1.86)points of the control group,and the difference was statistically significant(t=11.102,P<0.05).Conclusion Chaihu plus Longgu Muli Decoction combined with zopiclone tablets can significantly improve the sleep quality and neurological function of patients of ischemic stroke.