探讨外周血D-二聚体对急性脑梗死体积的预测价值

Predictive Value Exploration of Peripheral Blood D-Dimer for Acute Cerebral Infarction Volume

目的探讨外周血D-二聚体对急性脑梗死体积的预测价值。方法对2021年6月—2023年6月发病时间在72h内送入本院的105例急性脑梗死患者进行观察,并根据患者的头颅MRI检查结果将其划分为大体积组(n=31)、中体积组(n=48)、小体积组(n=26)。将三组患者的资料进行比较,分析D-二聚体对急性脑梗死体积的预测价值。结果小体积组、中体积组各项检查结果优于大体积组,差异有统计学意义(P<0.05);小体积组D-二聚体、PFDs优于中体积组,总胆红素和直接胆红素指标对比,两组差异无统计学意义(P>0.05)。小体积组患者神经功能评分优于中体积组、大体积组,差异有统计学意义(P<0.05)。结论外周血D-二聚体对急性脑梗死体积具有一定的预测价值,可以作为对患者梗死体积进行预测的一种辅助方式。

Objective To explore predictive value of peripheral blood D-dimer for volume of acute cerebral infarction.Methods The paper observed 105 patients with acute cerebral infarction within 72 hours of onset in our hospital from June 2021 to June 2023,and divided them into large volume group(n=31),medium volume group(n=48),and small volume group(n=26)based on results of head MRI examination.Data of three groups were compared,predictive value of D-dimer for acute cerebral infarction volume was analyze.Results There were significant differences in infarct volume and nerve function scores among the three groups(P<0.05).There were significant differences in D-dimer,PFDs,total bilirubin and direct bilirubin between large volume group and small large volume group(P<0.05).There was no significant difference in total bilirubin and direct bilirubin between small and medium volume groups(P>0.05).Conclusion Peripheral blood D-dimer has certain predictive value for volume of acute cerebral infarction and can be an auxiliary method for predicting infarct volume of patients.