OSAHS与高血压、焦虑、抑郁的相关性研究进展

Research progress on the correlation of obstructive sleep apnea hypopnea syndrome with hypertension,anxiety,and depression

阻塞性睡眠呼吸暂停低通气综合征(OSAHS)是最常见的睡眠障碍类型,随着研究的不断深入,其发现OSAHS患者常合并高血压、焦虑、抑郁等疾病。事实上,这些疾病具有不同的生物学机制和危险因素,表明它们之间存在潜在的双向关联,但目前对这些疾病之间的联系尚不明确,精神疾病和OSAHS的症状(疲劳、白天嗜睡、淡漠等)之间存在重叠,导致临床上诊断及治疗困难。本文将阐述OSAHS与高血压、焦虑、抑郁的病理生理机制、治疗及预后,为临床诊疗提供参考依据及思路。

Obstructive sleep apnea hypopnea syndrome(OSAHS)is the most common type of sleep disorder,and it is found that the OSAHS patients are often combined with diseases such as hypertension,anxiety,and depression.In fact,these diseases have different biological mechanisms and risk factors,indicating that there is a potential bidirectional association between them.However,the link between these diseases is not clear.There is overlap between mental disorders and OSAHS symptoms(fatigue,daytime sleepiness,apathy,etc.),leading to difficulties in clinical diagnosis and treatment.This article will elaborate on the pathophysiological mechanism,treatment,and prognosis of OSAHS with hypertension,anxiety,or depression,and provide reference and ideas for clinical diagnosis and treatment.