运动训练对AD源性轻度认知功能障碍的影响研究

Effect Research of Exercise Training on AD Induced Mild Cognitive Impairment

目的研究运动训练对阿尔茨海默病源性轻度认知功能障碍的影响。方法选取2021年6月—2023年1月在本市老年病医院门诊诊断为阿尔茨海默病(Alzheimer's disease,AD)源性的轻度认知功能障碍(MCI)老年患者122例,按照随机数表法将其分为对照组(n=61)和观察组(n=61)。对照组采用常规治疗方案;观察组在对照组的常规干预基础上增加多组分运动锻炼,包括抗阻运动、有氧运动、平衡训练及柔韧性训练,一周3次,每次45-60min。结果采用运动训练后,实验组与对照组相比,ADL、MMSE、SPPB、TUGT评分均有明显提升(P<0.05)。结论运动训练对AD源性轻度认知功能障碍有正向影响。

Objective To investigate effect of exercise training on mild cognitive impairment caused by Alzheimer's disease.Methods The paper chose 122 elderly patients with AD induced MCI in geriatric outpatient department of the city from June 2021 to January 2023,and divided them into control group(n=61)and observation group(n=61)with random number table method.Control group was treated with routine treatment,and observation group with multi-component exercise on the basis of routine intervention of control group,including resistance exercise,aerobic exercise,balance training and flexibility training,three times a week for 45-60 minutes each time.Results After exercise training,experimental group showed more significant improvement in ADL,MMSE,SPPB,and TUGT scores than control group(P<0.05).Exploration:Exercise training can achieve positive effect on AD induced mild cognitive impairment.