非酒精性脂肪肝患者血清透明质酸水平与肝功能Child分级的关系

Predictive value of serum HA levels in non-alcoholic fatty liver patients with different liver function states on the risk of liver cancer within five years

目的分析非酒精性脂肪肝患者血清透明质酸水平与肝功能Child分级的关系。方法选择陕西省人民医院2017年1月至2018年9月收治的非酒精性脂肪肝患者110例作为研究对象,依据Child的分级标准Child A级组23例、Child B级组52例、Child C级组35例。比较三组性别、年龄、体质指数、血清透明质酸水平。结果Child A级组、Child B级组和Child C级组的性别、年龄、体质指数比较差异均无统计学意义(P>0.05)。Child C级组血清透明质酸水平(91.39±24.67)高于Child B级组(38.26±9.36)和Child A级组(29.55±6.97),差异均有统计学意义(P<0.05);而Child B级组(38.26±9.36)和Child A级组(29.55±6.97)血清透明质酸水平比较差异无统计学意义(P>0.05)。结论肝功能差的非酒精性脂肪肝患者血清透明质酸水平高。

Objective To analyze the relationship between serum hyaluronic acid levels and Child classification of liver function in Steatosis patients.Methods A total of 110 Steatosis patients admitted to Shaanxi People′s Hospital from January 2017 to September 2018 were selected There were 23 cases in Child a group,52 cases in Child B group and 35 cases in Child C Group.Sex,age,body mass index(BMI)and serum hyaluronic acid(ha)were compared among the three groups.Results There were no significant differences in sex,age and BMI among Child A,Child B and Child C groups(P>0.05).The level of serum hyaluronic acid in Child class C(91.39±24.67)was significantly higher than that in Child class B(38.26.9.36)and Child class A(29.55±6.97)(P<0.05).There was no significant difference in serum hyaluronic acid levels between Child B(38.26.9.36)and Child A(29.55±6.97)groups(P>0.05).Conclusion Serum hyaluronic acid levels are high in Steatosis patients with poor liver function.